Results 121 to 130 of about 274,382 (304)

Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes. [PDF]

iScience, 2023
Yadav PS, Papaioannou G, Kobelski MM, Demay MB.   +3 more
europepmc   +1 more source

Characterization of a Novel Isoform of Caspase-9 That Inhibits Apoptosis [PDF]

, 2001
James M. Angelastro, Nah Yong Moon, David X. Liu, An‐Suei Yang, Lloyd A. Greene, T. Franke   +5 more
openalex   +1 more source

Induction of Nephron–Ductal Dual Lineages via Early Retinoic Acid Signaling Establishes a Platform for Fully Patterned Kidney Organoids

Advanced Healthcare Materials, EarlyView.
A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim, Seeun Kim, Dong Hyun Lee, Dae Hun Kim, Hye Bin Lee, Ye Seul Son, Mi‐Young Son, Soo Jin Oh, Ji‐Yoon Lee, Mi‐Ok Lee, Hyun Soo Cho, Dae‐Soo Kim, Cho‐Rok Jung, Hyun Mi Kang   +13 more
wiley   +1 more source

A Unique Downstream Estrogen Responsive Unit Mediates Estrogen Induction of Proteinase Inhibitor-9, a Cellular Inhibitor of IL-1β- Converting Enzyme (Caspase 1) [PDF]

, 2001
Sacha A. Krieg, Adam J. Krieg, David J. Shapiro   +2 more
openalex   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Inducible caspase 9-mediated suicide gene therapy using AAV6 vectors in a murine model of breast cancer. [PDF]

Mol Ther Methods Clin Dev, 2023
Pathak S, Singh V, Kumar N, Jayandharan GR.   +3 more
europepmc   +1 more source

Oxidative stress and increased levels of apoptosis (Cytochrome C, Caspase 3 and 9) in patients with male-factor infertility. [PDF]

, 2001
X Wang, Rakesh Sharma, Pavithra Ranganathan, A.J. Thomas, Tommaso Falcone, Ashok Agarwal   +5 more
openalex   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Caspase-9 inhibition triggers Hsp90-based chemotherapy-mediated tumor intrinsic innate sensing and enhances antitumor immunity. [PDF]

J Immunother Cancer, 2023
Li J, Han X, Sun M, Li W, Yang G, Chen H, Guo B, Li J, Li X, Wang H, Wang H.   +10 more
europepmc   +1 more source

Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation after Transient Focal Cerebral Ischemia in Mice [PDF]

, 2001
Nobuo Noshita, Taku Sugawara, Miki Fujimura, Yuiko Morita‐Fujimura, Pak H. Chan   +4 more
openalex   +1 more source