Results 251 to 260 of about 4,742,958 (308)

Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells [PDF]

, 2003
Salmaan H. Inayat‐Hussain, B.O Annuar, Laily B. Din, Abdul Manaf Ali, David Ross   +4 more
openalex   +1 more source

Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome

Proceedings of the National Academy of Sciences of the United States of America, 2014
Q. Hu, Di Wu, Wen Chen, Zhen Yan, Chuangye Yan, Tianxi He, Qiong-lin Liang, Yigong Shi   +7 more
semanticscholar   +1 more source

Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B. [PDF]

Front Immunol, 2021
Klopp A, Schreiber S, Kosinska AD, Pulé M, Protzer U, Wisskirchen K.   +5 more
europepmc   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source

Down-Regulation of Monocyte Apoptosis by Phagocytosis of Platelets: Involvement of a Caspase-9, Caspase-3, and Heat Shock Protein 70-Dependent Pathway

, 2002
Detlef Lang, Frank Dohle, Martin Terstesse, Philip Bangen, Christian August, Hans‐Gerd Pauels, Stefan Heidenreich   +6 more
openalex   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Taurine Monochloramine Activates a Cell Death Pathway Involving Bax and Caspase-9 [PDF]

, 2004
Derek K. Emerson, Michael L. McCormick, Jennifer A. Schmidt, C. Michael Knudson   +3 more
openalex   +1 more source

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis

Animal Models and Experimental Medicine, EarlyView.
The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome, Ilva D. Rupenthal, Rachael L. Niederer, Odunayo O. Mugisho   +3 more
wiley   +1 more source

Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor [PDF]

, 2004
Nisha Shah, Rebecca J. Asch, Alana S. Lysholm, Tucker W. LeBien   +3 more
openalex   +1 more source