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Polymorphisms of Caspase 8 and Caspase 9 gene and colorectal cancer susceptibility and prognosis
International Journal of Colorectal Disease, 2011Caspase-8 (CASP8) and caspase-9 (CASP9) play crucial roles in regulating apoptosis, and their functional polymorphisms may alter cancer risk. Our aim was to investigate the association between CASP8 and CASP9 gene polymorphisms and colorectal cancer (CRC) susceptibility.A case-control study at 402 CRC patients and 480 healthy controls was undertaken in
Anna Vaiopoulou +7 more
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The Regulation of the Alternative Splicing of Caspase 9
2010VCU Theses and ...
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Analysis of Apaf-1 and Caspase 9 in Tumorigenesis [PDF]
, 2002 Abstract : The replicative exhaustion of Human diploid fibroblasts (HDFs) in culture is associated with an "irreversible" cell-cycle arrest known as replicative senescence. However, young cells can enter a similar phenotype to replicative senescence in response to expression of certain mitogenic oncogenes, oxidative stress, and DNA damage.
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SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation
Signal Transduction and Targeted Therapy, 2020Jun Shen, Shi Zhengli, Peng Zhou
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature, 2015Nobuhiko Kayagaki +2 more
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Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
Nature, 2019Lars M Schiffmann, , Martin Krönke
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Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome
Nature Catalysis, 2020Bas J H M Rosier +2 more
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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
Nature, 2004Sanjeev Mariathasan +2 more
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