Results 241 to 250 of about 135,991 (300)

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +1 more source

Pyroptosis-induced tissue damage in kidney disease. [PDF]

open access: yesRen Fail
Zhang Z, Li X, Han Y, Zhang M.
europepmc   +1 more source

Preventive Role of Simvastatin against Infertility: Potential Role of PGC-α/PPARβ/UCPs and NF-κβ Signaling Pathways. [PDF]

open access: yesInt J Prev Med
Motaghinejad O   +5 more
europepmc   +1 more source

Profiling the Expression Level of a Gene from the Caspase Family in Triple-Negative Breast Cancer. [PDF]

open access: yesInt J Mol Sci
Makuch-Kocka A   +6 more
europepmc   +1 more source

Impaired NLRP3 inflammasome signaling diverts pyroptotic to apoptotic caspase activation in macrophages. [PDF]

open access: yesFront Immunol
Gan YQ   +13 more
europepmc   +1 more source

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