Results 121 to 130 of about 29,420 (294)

Fighting Emerging Caspofungin-Resistant Candida Species: Mitigating Fks1-Mediated Resistance and Enhancing Caspofungin Efficacy by Chitosan

Antibiotics
Invasive candidiasis poses a worldwide threat because of the rising prevalence of antifungal resistance, resulting in higher rates of morbidity and mortality. Additionally, Candida species, which are opportunistic infections, have significant medical and
Aya Tarek, Yasmine H. Tartor, Mohamed N. Hassan, Ioan Pet, Mirela Ahmadi, Adel Abdelkhalek   +5 more
doaj   +1 more source

Neonatal Cholestasis Progressing to a Multisystem Syndrome With Liver Cirrhosis in Two Siblings With FARSA Deficiency: An Evolving Hepatological Phenotype

JIMD Reports, Volume 66, Issue 3, May 2025.
ABSTRACT Biallelic variants in FARSA or FARSB are associated with reduced cytoplasmic phenylalanyl‐tRNA synthetase (FARS1) activity and underlie a multisystem syndrome characterized by growth limitation, developmental delay, brain calcifications, interstitial lung disease (ILD), and liver involvement.
Y. Aelvoet, P. Verloo, A. Vanlander, S. Vande Velde, S. Van Biervliet, P. De Bruyne, L. Hoste, A. Dheedene, L. Pottie, A. Hoorens, M. Mendes, R. De Bruyne   +11 more
wiley   +1 more source

Impact of Invasive Fungal Diseases on Treatment Outcomes in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: Insights From a Single‐Center Study

Pediatric Blood &Cancer, Volume 72, Issue 5, May 2025.
ABSTRACT Background and Aims Invasive fungal diseases (IFD) in children with newly diagnosed acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) are poorly characterized, especially in lower–middle‐income countries (LMICs). This study aims to identify the incidence, risk factors, and outcomes of IFD in a pediatric cohort with ALL/LBL ...
Amrutha Narayana Murthy, Shyam Srinivasan, Vasundhara Patil, Gaurav Salunke, Chetan Dhamne, Nirmalya Roy Moulik, Maya Prasad, Badira C Parambil, Venkata Rama Mohan Gollamudi, Akanksha Chichra, Girish Chinnaswamy, Gaurav Narula, Shripad Banavali   +12 more
wiley   +1 more source

Intravitreales Caspofungin bei Pilzendophthalmitis

, 2016
Hintergrund: Capsofungin (CANCIDAS, MSD) ist ein neueres synthetisches Mykostatikum mit sehr guter Wirksamkeit gegen Candida und Aspergillus Species. Bei parenteraler Anwendung hat es ein deutlich geringes Nebenwirkungsspektrum als Amphotericin B.
von Jagow, B, Niederstadt, C
openaire   +2 more sources

In Vitro Assessment of Antifungal Caspofungin on Leishmania donovani Culture Isolation

Canadian Journal of Infectious Diseases and Medical Microbiology, 2017
Leishmania parasite isolation from the human aspirates is always challenging due to most probability of the fungal contamination and the use of antifungal drug which could support the selective growth of the Leishmania parasite. In this study, we examine
Narayan Raj Bhattarai, Keshav Rai, Suman Rijal, Basudha Khanal   +3 more
doaj   +1 more source

Synergistic effect of nikkomycin Z with caspofungin and micafungin against Candida albicans and Candida parapsilosis biofilms

Letters in Applied Microbiology, 2019
Antifungal lock therapy has received significant interest in the last few years because the frequently usage of intravascular devices is associated with an increasing number of catheter‐related bloodstream infections caused by Candida species. Antifungal
R. Kovács, F. Nagy, Zoltán Tóth, Aliz Bozó, Bence Balázs, L. Majoros   +5 more
semanticscholar   +1 more source

Fungal infections today: size of the problem and focus on the initial cost of therapy with echinocandin

Farmeconomia: Health Economics and Therapeutic Pathways, 2010
Three candins had been approved for the treatment of invasive candidiasis (IC): caspofungin, micafungin, and anidulafungin. Different drugs are associated with different needs for dose adjustment which might affect the total cost.
Mario Venditti
doaj   +1 more source

Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels

Antimicrobial Agents and Chemotherapy, 2019
Caspofungin has a liver-dependent metabolism. Reduction of the dose is recommended based on Child-Pugh (C-P) score. ABSTRACT Caspofungin has a liver-dependent metabolism. Reduction of the dose is recommended based on Child-Pugh (C-P) score. In critically
Siri Kurland, M. Furebring, E. Löwdin, Erik Eliasson, Elisabet I Nielsen, J. Sjölin   +5 more
semanticscholar   +1 more source

The Effects of Holothurin and Caspofungin on the Vaginal Cell Inflammation Parameters of the Rattus norvegicus Strain Post Induction of Candida albicans

Infection and Drug Resistance, 2023
Sri Handayani,1,2 Nurdiana Nurdiana,3 Sri Winarsih,4 Agustina Tri Endharti5 1Doctoral Program of Medical Science Department, Faculty of Medicine, Brawijaya University, Malang, Indonesia; 2Department of Midwifery of Aisyiyah, Institution of Surakarta ...
Handayani S, Nurdiana N, Winarsih S, Tri Endharti A   +3 more
doaj  

[Clinical and juridical aspects of management of neonates with invasive fungal infections] [Article in Italian] • Aspetti clinici e giuridici della gestione del neonato con infezioni fungine invasive

Journal of Pediatric and Neonatal Individualized Medicine, 2012
Fungal infections are an important cause of morbidity and mortality in neonatology, especially in the case of neonates weighing ≤ 1500 grams (VLBW) at birth.
Vassilios Fanos, Angelica Dessì, Riccardo Fresa   +2 more
doaj   +1 more source