Results 101 to 110 of about 16,636 (201)

Effi cacy and safety of caspofungin in obese patients

, 2011
patient weight is a factor in determining dosing for some other antifungal agents (e.g., poylene formulations [1]). Hence, questions have arisen regarding use of weight as a factor in determining caspofungin dosing for obese adults.
Desmond M. Ryan, Nicholas A. Kartsonis, Robert J. Lupinacci   +2 more
core   +1 more source

Caspofungin versus anidulafungin in patients with invasive candidiasis: a retrospective study with propensity-score-matched analysis

Therapeutic Advances in Infectious Disease
Background: Echinocandins are recommended as an initial treatment for invasive candidiasis. Although safety and efficacy profiles of both anidulafungin and caspofungin are well established, direct head-to-head comparisons have not been reported before ...
Reem Hasan Elajez, Dana Bakdach, Sara Al Balushi, Ahmed Zaqout, Rand Alattar, Tasneem Abdallah, Waleed Awouda, Godwin Wilson, Walid Al-Wali, Emad Ibrahim, Hussam Alsoub   +10 more
doaj   +1 more source

Comparison of Vitek 2C antifungal susceptibility testing with broth microdilution testing for Candida species [PDF]

Medical Laboratory Journal
Background: The reference method for antifungal susceptibility testing is broth microdilution according to Clinical and Laboratory Standard Institute (CLSI) guidelines.
Sukanya Sudhaharan, Naga Appala Raju Sundarapu, Umabala Pamidimukkala   +2 more
doaj  

Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris

, 2019
DigitalBackground: Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Morales López, Soraya, Gamarra, Soledad, Theill, Laura, Macedo, Daiana, Dudiuk, Catiana, Leonardelli, Florencia, Rodríguez, José-Yesid, Berrio, Indira, Salcedo, Soraya, Marín, Adriana, Garcia Effron, Guillermo   +10 more
core   +1 more source

Compensatory response of the cell wall integrity pathway and chitin to caspofungin exposure in Candida glabrata

, 2007
Background: Studies in Saccharomyces cerevisiae and Candida albicans have reported an up-regulation of the cell wall integrity pathway and an increase in cell wall chitin following caspofungin exposure.
Cota, Jason M.
core   +1 more source

Overexpression of Sbe2p, a Golgi Protein, Results in Resistance to Caspofungin in Saccharomyces cerevisiae

, 2002
Caspofungin inhibits the synthesis of 1, 3-β- d -glucan, an essential cell wall target in fungi. Genetic studies in the model yeast Saccharomyces cerevisiae have shown that mutations in FKS1
Nir Osherov, Gregory S. May, Nathaniel D. Albert, D. P. Kontoyiannis   +3 more
core   +1 more source

Caspofungin Combined With TMP/SMZ in Treatment of Intractable Acute Pneumocystis jirovecii Pneumonia in Renal Transplant Recipients: Case Report and Literature Review

Clinical Case Reports
Pneumocystis jirovecii pneumonia (PJP) is a potential life‐threatening opportunistic infection that predominantly affects immunocompromised individuals, such as those with human immunodeficiency virus or organ transplant recipients. The treatment of PJP,
Hongtao Hu, Shen Xu, Wen Jiang, Baoping Xu, Jing Wang, Gang Xu   +5 more
doaj   +1 more source

HEPATIC UPTAKE OF THE NOVEL ANTIFUNGAL AGENT CASPOFUNGIN

, 2005
Inc.) is a novel echinocandin antifungal agent used in the treatment of esophageal and invasive candidiases, invasive aspergillosis, and neutropenia. Available data suggest that the liver is a key organ responsible for caspofungin elimination in rodents ...
Richard B. Kim, Yamazaki, Masayo, Xin Xu, Paul G. Pearson, Julie A. Stone, Stone, Julie A., Brenda F. Leake, Wooin Lee, Xu, Xin, Masayo Yamazaki, Pearson, Paul G., Kim, Richard B., Sandhu, Punam, Lee, Wooin, Lin, Jiunn H., Jiunn H. Lin, Punam S, Leake, Brenda F.   +17 more
core   +1 more source

Caspofungin [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

Ocular penetration of caspofungin in a rabbit uveitis model [PDF]

, 2018
Background: Little is known about the ocular penetration of echinocandin antifungals. We studied the ocular distribution of systemically administered caspofungin in a rabbit uveitis model.
Zimmerli, Stefan, Goldblum, David, Thormann, Wolfgang, Theurillat, Regula, Frueh, Beatrice, Fausch, Kathrin   +5 more
core