Results 91 to 100 of about 16,636 (201)

Development and Quality Control of a Population Pharmacokinetic Model Library for Caspofungin

Pharmaceutics
Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections.
Nuo Xu, Yufei Shi, Yixue Wang, Wenyao Mak, Wenyu Yang, Kar Weng Ng, Yue Wu, Zhijia Tang, Qingfeng He, Gangfeng Yan, Xiaoqiang Xiang, Xiao Zhu   +11 more
doaj   +1 more source

Caspofungin in pediatric patients

, 2008
Invasive fungal infections have emerged as one of the most significant complications in severely immunocompromised pediatric patients, such as children suffering from hematological malignancies or children undergoing hematopoietic stem cell ...
Andreas H Groll, Thomas Lehrnbecher
core   +1 more source

Caspofungin in vivo hatékonysága Candida parapsilosis, Candida orthopsilosis és Candida metapsilosis izolátumok ellen neutropéniás egérmodellben

, 2012
Az utóbbi években a neutropéniás betegek esetében a Candida albicans mellett, a nem albicans fajok is megjelentek mint a C. parapsilosis, amelyen belül molekuláris biológiai módszerek segítségével másik két fajt: a Candida orthopsilosist és a C ...
Joó, Imre
core  

Sensitivity of the CnaA truncation strains to Caspofungin.

, 2013
CnaA truncation expression strains were cultured on GMM agar in the presence of varying concentrations of the cell wall inhibitor caspofungin for 5 days.
Praveen R. Juvvadi (449281), Trevor P. Creamer (36175), Christopher Gehrke (449282), Yohannes G. Asfaw (449286), M. Arthur Moseley (202620), Michael A. Hast (449285), Frédéric Lamoth (352803), William J. Steinbach (449287), Jarrod R. Fortwendel (449283), Erik C. Cook (449284), Erik J. Soderblom (323225)   +10 more
core   +1 more source

Application of caspofungin in China compared with amphotericin B and fluconazole

, 2014
Chunyu Zhang,1 Jiaoying Cheng,2 Yan Jiang,3 Junyang Liu41Department of Health Reform and Development, China–Japan Friendship Hospital, Beijing, People’s Republic of China; 2Department of Obstetrics and Gynecology, China–Japan Friendship
Jiang Y, Liu JY, Cheng JY, Zhang CY
core  

Pharmacokinetics of Caspofungin Acetate in Healthy Adult Cats [PDF]

, 2018
Background Sino-orbital aspergillosis (SOA) is an invasive fungal infection with high mortality due to difficulty in its treatment. SOA is commonly caused by cryptic species in Aspergillus section Fumigati that are often resistant to antifungal triazoles
Leshinsky, Jana
core  

Detection of Caspofungin Resistance in Candida spp. by Etest

, 2008
International audienceThe caspofungin susceptibilities of 28 Candida sp. clinical isolates, including 8 caspofungin-resistant isolates characterized by mutations in the Fks1 protein, were determined by the Etest in RPMI and AM3 media. Good discrimination
Desnos-Ollivier, Marie, Dannaoui, Eric, Dromer, Françoise   +2 more
core   +1 more source

Pharmacokinetics of caspofungin acetate to guide optimal dosing in cats.

, 2017
Cats are the most common mammal to develop invasive fungal rhinosinusitis caused by cryptic species in Aspergillus section Fumigati that are resistant to azoles but susceptible to caspofungin.
David J. R. Foster, Foster, DJR, Norris, Ross, Vanessa R. Barrs, McLachlan, A, Barrs, VR, Jana Leshinsky, David J R Foster, Leshinsky, J, McLachlan, Andrew, Norris, R, Barrs, Vanessa R., Foster, David J. R., Andrew McLachlan, Vanessa R Barrs, Leshinsky, Jana, Ross Norris   +16 more
core   +1 more source

Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study

This study aimed to describe the population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation (ECMO) and to identify dosing regimens with a high likelihood of achieving effective exposures.
McGuinness, Shay, Roberts, Jason A, Shekar, Kiran, Pellegrino, Vincent, Levkovich, Bianca, Gilder, Eileen, Ordonez, Jenny, Diehl, Arne, Wallis, Steven C, Parke, Rachael, Abdul-Aziz, Mohd H, Liu, Xin, Fraser, John F, Corley, Amanda, Cheng, Vesa   +14 more
core   +1 more source

Enhanced efficacy of synergistic combinations of antimicrobial peptides with caspofungin versus Candida albicans in insect and murine models of systemic infection

, 2013
The objective of this study was to determine whether combinations of antimicrobial peptides (AMPs) with caspofungin display enhanced antifungal activity versus Candida albicans in vitro and in vivo.
Coote, Peter John, MacCallum, Donna, Desbois, Andrew P, MacCallum, Donna M, Desbois, Andrew, Coote, Peter J   +5 more
core   +1 more source