Background. Invasive aspergillosis (IA) is an important cause of morbidity and mortality among immuno-compromised patients. Echinocandins are novel antifungal molecules with in vitro and in vivo activity against Aspergillus species. Methods.
Walsh, TJ +14 more
core
Caspofungin is the first approved agent from a class of antifungal agents called the echinocandins. Its mechanism of action is unique in that it attacks the cell wall of the fungus, as opposed to its cell membrane.
Joel M. Weinstein, MD
core
Fpr1p mediates the synergistic effect of rapamycin or tacrolimus with caspofungin in <i>Clavispora lusitaniae in vitro</i>. [PDF]
Lefranc M +4 more
europepmc +1 more source
Caspofungin-Based Red-Emissive Probes for Fluorescent Imaging of Pathogenic Fungi. [PDF]
Klausen M +4 more
europepmc +1 more source
Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene. [PDF]
Takehara M +10 more
europepmc +1 more source
Immunological fitness of echinocandin-resistant <i>Nakaseomyces glabratus</i> (former <i>Candida glabrata</i>): The impact on the management of candidemia. [PDF]
Basmaciyan L +11 more
europepmc +1 more source
Correction: Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis. [PDF]
Wu Y +9 more
europepmc +1 more source
Evaluation of Sensititre YeastOne for antifungal susceptibility testing of <i>Candida (Candidozyma) auris</i>: misclassification of <i>FKS1</i> mutants and overestimation of caspofungin resistance in a global collection of isolates. [PDF]
Siopi M +11 more
europepmc +1 more source
Harnessing random peptide mixtures to combat multidrug-resistant fungal infections. [PDF]
Adeoye J +6 more
europepmc +1 more source

