Results 121 to 130 of about 28,829 (241)

Predictors of caspofungin exposure-response relationship: a retrospective cohort study on therapeutic drug monitoring parameters

Frontiers in Pharmacology
IntroductionThis study aimed to characterize the exposure-response relationship of caspofungin through analysis of trough serum concentration (Cmin) associated with clinical efficacy, while identifying clinically determinants of Cmin.MethodsA single ...
Mingwei Meng, Ruhua Wei, Yating Lu, Wen Cao, Kai Mo, Zheng Huang, Yane Qin, Xiaobu Lan   +7 more
doaj   +1 more source

[Clinical and juridical aspects of management of neonates with invasive fungal infections] [Article in Italian] • Aspetti clinici e giuridici della gestione del neonato con infezioni fungine invasive

Journal of Pediatric and Neonatal Individualized Medicine, 2012
Fungal infections are an important cause of morbidity and mortality in neonatology, especially in the case of neonates weighing ≤ 1500 grams (VLBW) at birth.
Vassilios Fanos, Angelica Dessì, Riccardo Fresa   +2 more
doaj   +1 more source

Variability in antifungal and antiviral use in hospitalized children [PDF]

, 2017
We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S, Goldman, Jennifer L, Hersh, Adam L, Kronman, Matthew P, Lee, Brian R, Newland, Jason G, Ross, Rachael K   +6 more
core   +2 more sources

Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels

Antimicrobial Agents and Chemotherapy, 2019
Caspofungin has a liver-dependent metabolism. Reduction of the dose is recommended based on Child-Pugh (C-P) score. ABSTRACT Caspofungin has a liver-dependent metabolism. Reduction of the dose is recommended based on Child-Pugh (C-P) score. In critically
Siri Kurland, M. Furebring, E. Löwdin, Erik Eliasson, Elisabet I. Nielsen, J. Sjölin   +5 more
semanticscholar   +1 more source

Development and Quality Control of a Population Pharmacokinetic Model Library for Caspofungin

Pharmaceutics
Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections.
Nuo Xu, Yufei Shi, Yixue Wang, Wenyao Mak, Wenyu Yang, Kar Weng Ng, Yue Wu, Zhijia Tang, Qingfeng He, Gangfeng Yan, Xiaoqiang Xiang, Xiao Zhu   +11 more
doaj   +1 more source

Anti-infective surface coatings: design and therapeutic promise against device-associated infections [PDF]

, 2016
Patient safety and well-being are under increasing threat from hospital-acquired infections [1]. The root cause of a large number of these infections arises from microbial biofilms that colonise on surfaces of medical devices such as the millions of ...
Coad, B., Griesser, H., Peleg, A., Traven, A.   +3 more
core   +1 more source

New cell wall-affecting antifungal antibiotics [PDF]

, 2013
Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G., Durán, Ángel, Ribas, Juan Carlos   +2 more
core   +2 more sources

Caspofungin resistance in Candidaalbicans: genetic factors and synergistic compounds for combination therapies

Brazilian Journal of Microbiology, 2022
F. Perrine-Walker
semanticscholar   +1 more source

Caspofungin for prevention of intra-abdominal candidiasis in high-risk surgical patients [PDF]

, 2018
Purpose: Thirty to forty percent of patients with recurrent gastrointestinal perforation/anastomotic leakage or acute necrotizing pancreatitis develop intra-abdominal invasive candidiasis (IC).
Bille, Jacques, Calandra, Thierry, Demartines, Nicolas, Eggimann, Philippe, Ksontini, Riadh, Marchetti, Oscar, Pascual, Andres, Senn, Laurence   +7 more
core  

Scedosporium prolificans Septic Arthritis [PDF]

, 2017
Scedosporium prolificans is an emerging fungal pathogen that can cause significant morbidity, and even mortality, in both immunocompromised and immunocompetent patients.
Frankenhoff, Jessica A., Isaacs, Jonathan E., Pace, Collier S.   +2 more
core   +1 more source