Results 91 to 100 of about 650,104 (308)
CancersBackground/Objectives: Progression to metastatic castration-resistant prostate cancer (mCRPC) is defined either biochemically, radiographically or both. Moreover, staging for mCRPC can be performed either conventionally or with molecular imaging such as prostate-specific membrane antigen computer tomography (PSMA-PET/CT).
Mike Wenzel +12 more
openaire +2 more sources
Abiraterone in the treatment of metastatic castration-resistant prostate cancer
, 2014 Elahe A Mostaghel Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Abstract: Androgen deprivation therapy remains the single most effective treatment for the initial therapy of advanced prostate cancer, but is ...
Mostaghel EA
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Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
BMEMat, EarlyView.This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Enzalutamide for the treatment of metastatic castration-resistant prostate cancer
, 2015 Alejo Rodriguez-Vida,1 Myria Galazi,1 Sarah Rudman,1 Simon Chowdhury,1 Cora N Sternberg2 1Medical Oncology Department, Guy’s and St Thomas’ NHS Foundation Trust, London, UK; 2Medical Oncology Department, San Camillo and Forlanini Hospitals ...
Galazi M +4 more
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, 2015 Androgen targeted therapies\ud (ATT) are the most commonly used treatments\ud in prostate cancer (PCa).While\ud these therapies are initially effective, PCa cells are able to activate adaptive response\ud pathways to survive these therapies and\ud ...
Hollier, Brett G. +5 more
core +1 more source
Interdisciplinary Medicine, EarlyView.In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang +11 more
wiley +1 more source
Scientific ReportsThis nationwide register-based cohort study examined the association between castration status and postoperative survival in men who had undergone surgery for spinal metastases from prostate cancer. Bone metastases are common in prostate cancer, with the
Johan Wänman +6 more
doaj +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives
iRADIOLOGY, EarlyView.This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo +6 more
wiley +1 more source
Economics of boar taint prevention without surgical castration in the pork chain
, 2010 An economic analyses of boar taint prevention without surgical castration is lacking. This paper explores currently feasible alternatives to surgical castration along the pork chain.
Backus, G.B.C. +4 more
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