Results 91 to 100 of about 36,345 (262)

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

open access: yesUroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

open access: yesNature Communications, 2018
The functional significance of the observed heterogeneity of androgen receptor (AR) expression in prostate cancer is unknown. Here the authors show AR expression heterogeneity is associated with distinct castration/enzalutamide responses and identify BCL-
Qiuhui Li   +24 more
doaj   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

‘Everything is a signal’: speaking circuits and noisy signs in the making of language‐oriented AI « Tout est signal » : circuits parlants et signes bruyants dans la création de l'IA orientée langage

open access: yesJournal of the Royal Anthropological Institute, EarlyView.
Contemporary artificial intelligence (AI) technologies are often presumed to be capable of revealing unmediated truths about the world, including the truths language might hold, echoing the long‐standing assertion that language's primary function is to directly translate reality.
Beth M. Semel
wiley   +1 more source

Queering Institutional Milestones in Elite Higher Education: Queer Perspectives on Princeton University and Coeducation (1960–1980)

open access: yesGender &History, EarlyView.
ABSTRACT A new archive of oral history interviews from LGBTQIA‐identified alumni, faculty and staff reveals the complex ways that queer and transgender students understood, experienced and remembered the long transition from single‐sex to coeducation at Princeton University.
Ezelle Sanford III   +2 more
wiley   +1 more source

Histone Deacetylase Inhibitors Restore Cell Surface Expression of the Coxsackie Adenovirus Receptor and Enhance CMV Promoter Activity in Castration-Resistant Prostate Cancer Cells

open access: yesProstate Cancer, 2012
Adenoviral gene therapy using the death receptor ligand TRAIL as the therapeutic transgene can be safely administered via intraprostatic injection but has not been evaluated for efficacy in patients.
Laura Kasman   +2 more
doaj   +1 more source

Chemotherapy options in castration-resistant prostate cancer

open access: yesIndian Journal of Urology, 2016
The treatment landscape for patients with metastatic castration-resistant prostate cancer (CRPC) is evolving, with recent approvals of immune therapy, novel hormonal therapy, and bone-targeted therapy. Chemotherapy remains an essential component of the armamentarium.
Benjamin A Teply, Ralph J Hauke
openaire   +3 more sources

Cuttings, Combings, Fettlings and Flock: Gender and Australian Wool ‘Waste’, 1900–1950

open access: yesGender &History, EarlyView.
ABSTRACT As Australia's wool industry produced vast amounts of fine fleece from the nineteenth century, the wool processing and clothes manufacturing industries generated waste – products like cuttings, combings, fettlings and flock. Salvaged and then sold to waste merchants, these and other materials had a second life.
Lorinda Cramer
wiley   +1 more source

‘The Bethune College Sensation’: Gender, Archive and Radical Passivity

open access: yesGender &History, EarlyView.
ABSTRACT This article explores the student protests at Bethune College, Calcutta, on 3 February 1928, against the Simon Commission, a British parliamentary delegation that excluded Indian representation. On this day, female students staged a quiet but radical act of defiance by refusing to attend classes, sign apologies or vacate their hostel, despite ...
Meghmala Bhattacharya
wiley   +1 more source

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