Results 141 to 150 of about 219,417 (396)
The World Journal of Men's Health, 2023 Purpose: To analyze the variability, associated actors, and the design of nomograms for individualized testosterone recovery after cessation of androgen deprivation therapy (ADT).
Ángel Borque-Fernando +4 more
doaj +1 more source
Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]
, 2017 Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.
Cucchiara, Vito +5 more
core +2 more sources
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, EarlyView.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
wiley +1 more source
Emerging roles of BET proteins in transcription and co‐transcriptional RNA processing
WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023 Roles of BET proteins in RNA polymerase II transcription and co‐transcriptional RNA processing. Abstract Transcription by RNA polymerase II (Pol II) gives rise to all nuclear protein‐coding and a large set of non‐coding RNAs, and is strictly regulated and coordinated with RNA processing.
Nicole Eischer +2 more
wiley +1 more source
Animal, 2018 Immunocastration (ImC) has been proposed as an animal welfare-friendly alternative to reduce sexual and aggressive behavior and to increase carcass fat deposition with positive effects on meat quality.
D.J. Brigida +9 more
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Neuro-interventions as Criminal Rehabilitation: An Ethical Review [PDF]
, 2017 According to a number of influential views in penal theory, 1 one of the primary goals of the criminal justice system is to rehabilitate offenders. Rehabilitativemeasures are commonly included as a part of a criminal sentence.
Douglas, Thomas, Pugh, Jonathan
core
Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]
, 2017 Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S +31 more
core +1 more source
Anticancer Research, 2019 Background/Aim: It is important to delay the emergence of castration-resistant phenotype to improve the prognosis in patients with metastatic castration-sensitive prostate cancer (mCSPC).
H. Miyake +7 more
semanticscholar +1 more source
Drug Testing and Analysis, EarlyView.Triptorelin (5–10) confirmation using LC/MS‐IT‐TOF and LC‐Orbitrap can be used as evidence of triptorelin abuse in doping control. ABSTRACT Triptorelin, a synthetic gonadotrophin‐releasing hormone (GnRH), is mainly used in the clinical treatment of prostate cancer.
Navaporn Saardpun +6 more
wiley +1 more source
Immunocastration reduces aggressive and sexual behaviour in male pigs
Animal, 2010 The aim of this study was to evaluate the effectiveness of a gonadotropin-releasing hormone (GnRH) vaccine, Improvac™ (Pfizer Ltd), in suppressing aggressive and sexual behaviour of male pigs.
L. Rydhmer, K. Lundström, K. Andersson
doaj