Results 161 to 170 of about 219,417 (396)

Purple Yam Anthocyanin Forestalling Lipopolysaccharide‐Induced Intestine Damage by Selectively Promoting Lactococcus

open access: yesFood Frontiers, EarlyView.
Lipopolysaccharide‐induced oxidative stress results in intestine injury. The prophylactic oral anthocyanin and its fecal bacteria suspension can ameliorate the damage through the Lactococcus and metabolites, which lead to modulation of antioxidant‐ and inflammation‐related signaling pathways such as NF‐κB and Nrf2/Keap1, which in turn improves ...
Pingfei Qiu   +9 more
wiley   +1 more source

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor.

open access: yesACS Chemical Biology, 2016
Castration-resistant prostate cancer is the lethal condition suffered by prostate cancer patients that become refractory to androgen deprivation therapy.
E. de Mol   +12 more
semanticscholar   +1 more source

Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer

open access: yesInternational Brazilian Journal of Urology, 2010
PURPOSE: Complete androgen blockade (CAB) does not prolong overall survival (OS) in patients with castration refractory prostate cancer (CRPC). Although there is variable clinical benefit with second-line hormone manipulation, we do not know which ...
Rafael A. Kaliks   +3 more
doaj   +1 more source

Introduction [PDF]

open access: yes, 2018
Crime-preventing neurointerventions (CPNs) are increasingly being used or advocated for crime prevention. There is increasing use of testosterone-lowering agents to prevent recidivism in sexual offenders, and strong political and scientific interest in ...
Birks, David, Douglas, Thomas
core  

CUTANEOUS VASCULAR AND PIGMENTARY CHANGES IN CASTRATE AND EUNUCHOID MEN [PDF]

open access: bronze, 1941
Edward A. Edwards   +3 more
openalex   +1 more source

Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer.

open access: yesCancer Research, 2018
The standard treatment for metastatic prostate cancer, androgen deprivation therapy (ADT), is designed to suppress androgen receptor (AR) activity. However, men invariably progress to castration-resistant prostate cancer (CRPC), and AR reactivation ...
Joshua W. Russo   +13 more
semanticscholar   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

Economics of boar taint prevention without surgical castration in the pork chain [PDF]

open access: yes, 2010
An economic analyses of boar taint prevention without surgical castration is lacking. This paper explores currently feasible alternatives to surgical castration along the pork chain.
Backus, G.B.C.   +3 more
core   +1 more source

Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

open access: yesNature Network Boston, 2022
T. Powles   +19 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy