Results 41 to 50 of about 2,410,827 (326)
The LS category of the product of lens spaces [PDF]
We reduced Rudyak's conjecture that a degree one map between closed manifolds cannot raise the Lusternik-Schnirelmann category to the computation of the category of the product of two lens spaces $L^n_p\times L_q^n$ with relatively prime $p$ and $q$.
Dranishnikov, A.
core +2 more sources
Higgs Computed Axial Tomography, an excerpt. Taking a closer look at the camel-shaped tail of the light Higgs boson resonance and looking to the transformation of the (camel-shaped) signal into a square-root--shaped signal + interference with particular emphasis on residual theoretical uncertainties.
openaire +2 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
The role of cathepsin B, a lysosomal protease implicated in amyloid-beta (Abeta1-42) metabolism, in Alzheimer's disease remains controversial. In this issue of Neuron, Mueller-Steiner et al. manipulate the expression of cathepsin B in aged APP transgenic mice, observing that increased expression degrades preformed oligomeric and fibrillar amyloid ...
Cole, Greg M., Frautschy, Sally A.
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Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Many mammal species have declining populations, but the consequences of small population size on the genomic makeup of species remain largely unknown.
Liye Zhang+22 more
doaj +1 more source
Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. [PDF]
Cool-associated tyrosine-phosphorylated protein 1 (Cat-1) is a signaling scaffold as well as an ADP-ribosylation factor-GTPase-activating protein. Although best known for its role in cell migration, we recently showed that the ability of Cat-1 to bind ...
Antonyak, Marc A.+3 more
core +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Biocentrism and Marxism: Bloch’s Concept of Life and the "Spirit of Utopia"
This article argues that Ernst Bloch’s (1885-1977) early philosophical development was profoundly influenced by a biocentric perspective that dominated European culture in the decades around the turn of the twentieth century.
Cat Moir
doaj +1 more source
Comparison of predation by two suburban cats in New Zealand [PDF]
To study the effects domestic cats may have on surrounding wildlife, a complete list was made of 558 items caught in the garden or brought into the house by one cat over 17 years, from 1988 to 2005.
Flux, John E.C.
core +3 more sources