Results 101 to 110 of about 626,693 (336)

Ontologies, Mental Disorders and Prototypes [PDF]

, 2019
As it emerged from philosophical analyses and cognitive research, most concepts exhibit typicality effects, and resist to the efforts of defining them in terms of necessary and sufficient conditions.
A Lieto, American Psychiatric Association, American Psychiatric Association, Antonio Lieto, C Boorse, E Machery, E Rosch, E Rosch, G Murphy, I Horrocks, IR Galatzer-Levy, J Fodor, JC Wakefield, JC Wakefield, K Sadegh-Zadeh, K Sadegh-Zadeh, K Sadegh-Zadeh, L Wittgenstein, M Frixione, M Frixione, M Frixione, M Frixione, MC Amoretti, MC Amoretti, N Pickering, N Pickering, P Gärdenfors, R Brachman, R Cooper, R McNally, R Seising, SO Lilienfeld, SO Lilienfeld, W Ceusters   +33 more
core   +1 more source

1357. Collateral consequence of COVID pandemic: Increased incidence of cat scratch disease.

, 2022
Maria Laura Praino, Peditric Infectologist, Grigioni Julia, Peditric Infectologist, Soledad Tineo, Peditric Infectologist, Mayra Martinez, Ana Caratozzolo, Analía Toledano, Claudia I Cazes, Peditric Infectologist, María M Contrini, Eduardo López   +12 more
openalex   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Dating the Cryptococcus gattii Dispersal to the North American Pacific Northwest. [PDF]

, 2018
The emergence of Cryptococcus gattii, previously regarded as a predominantly tropical pathogen, in the temperate climate of the North American Pacific Northwest (PNW) in 1999 prompted several questions.
Bodo Wanke, Chandler C. Roe, Colleen Lysen, Crystal M. Hepp, David M. Engelthaler, David P. Overy, Emilio DeBess, George R. Thompson, Hanna Oltean, J. Andrew Alspaugh, Jolene Bowers, Philippe J. Dufresne, Scott McBurney, Shawn R. Lockhart, Tom Chiller, Wieland Meyer   +15 more
core   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The emerging disease occurrence of pet animals in Bangladesh

Journal of Advanced Veterinary and Animal Research, 2016
Objective: The objective of this study was to identify the current status of emerging diseases of pet animals in Bangladesh and to estimate the percentage of disease occurrence in the pet animals.
Umma Habiba, Rafiqul Islam, Mukter Hossain   +2 more
doaj   +1 more source

Glycogen storage disease in a young cat with heart failure [PDF]

, 2021
Shigeki Tanaka, Ryôhei Suzuki, Hidekazu Koyama, Noboru Machida, Akira Yabuki, Osamu Yamato   +5 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Emerging Viruses in the Felidae: Shifting Paradigms

Viruses, 2012
The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning ...
Meredith A. Brown, Jill Pecon-Slattery, Melody E. Roelke, Agostinho Antunes, Warren E. Johnson, Jennifer L. Troyer, Stephen J. O’Brien   +6 more
doaj   +1 more source