Results 61 to 70 of about 562,164 (234)

Feline leukaemia virus: half a century since its discovery [PDF]

, 2013
In the early 1960s, Professor William (Bill) F.H. Jarrett was presented with a timeGÇôspace cluster of cats with lymphoma identified by a local veterinary practitioner, Harry Pfaff, and carried out experiments to find if the condition might be caused by ...
Anderson, Benveniste, Benveniste, Brian J. Willett, Brown, Busch, Cunningham, de Beaumont, Draptchinskaia, Duffy, Filoni, Flynn, Flynn, Francis, Francis, Francis, Gomes-Keller, Gomes-Keller, Hardy, Helfer-Hungerbuehler, Helfer-Hungerbuehler, Hofmann-Lehmann, Hofmann-Lehmann, Hofmann-Lehmann, Hofmann-Lehmann, Hoover, Hoover, Jarrett, Jarrett, Jarrett, Jarrett, Jarrett, Jarrett, Jarrett, Jarrett, Johann, Johnson, Kawakami, Labay, Lewis, Luaces, Lutz, Mackey, Madewell, Marciani, Margaret J. Hosie, McDougall, Meli, Mendoza, Meyer, Onions, Osterhaus, Overbaugh, O’Hara, Pacitti, Pedersen, Poulet, Quigley, Quigley, Rey, Rickard, Riedel, Rigby, Roca, Roca, Rojko, Rojko, Roy-Burman, Sarma, Sarma, Schaller, Shalev, Sheets, Stewart, Stewart, Stewart, Tailor, Takeuchi, Tandon, Tartaglia, Theilen, Torres, Willig   +82 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Lesson of the week: Cat scratch disease

BMJ, 2002
Unilateral lymphadenopathy of the groin is commonly seen in general practice. We report on a patient with initial features suggestive of sarcoidosis, but who, after careful history taking and further investigation, had cat scratch disease. A 29 year old woman visited her general practitioner with a painless swelling in the right groin.
Terry Riordan, Alexander Williams, Christopher D Sheldon   +2 more
openaire   +4 more sources

Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan. [PDF]

, 2014
Background and objectives: Cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) commonly coexist and share common risk factors. The prevalence of COPD in outpatients with a smoking history and CVD in Japan is unknown.
Hagan, GW, Jones, PW, Onishi, K, Yoshimoto, D   +3 more
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

How to run a brain bank. A report from the Austro-German brain bank [PDF]

, 1993
The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way.
Gsell, W., Heckers, S., Heinsen, H., Jellinger, K., Lange, Klaus W., Pfeuffer, R., Ransmayr, G., Senitz, D., Vock, R., Wichart, I.   +9 more
core  

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang, Da Lin, Dongyuan Liu, Dongxu Zhang, Hao Wang   +4 more
wiley   +1 more source