Results 71 to 80 of about 636,485 (333)

Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco [PDF]

, 2012
The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in ...
Cardinal, Marta Victoria, Enriquez, Gustavo Fabián, Gurtler, Ricardo Esteban, Lanati, L., Orozco, Maria Marcela, Schijman, Alejandro Gabriel   +5 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Physical Activity Characteristics across GOLD Quadrants Depend on the Questionnaire Used [PDF]

, 2016
BACKGROUND:The GOLD multidimensional classification of COPD severity combines the exacerbation risk with the symptom experience, for which 3 different questionnaires are permitted.
A Agusti, A Agusti, AJ Viera, B Waschki, BE Garfield, C Casanova, Corina de Jong, D Shrikrishna, E Gimeno-Santos, E Gimeno-Santos, Elena Gimeno-Santos, F Pitta, GL Moreira, H Demeyer, H Van Remoortel, H Van Remoortel, H Van Remoortel, H Watz, Heleen Demeyer, Ioannis Vogiatzis, J Garcia-Aymerich, J Vestbo, JB Soriano, JB Soriano, JB Soriano, JC Bestall, Judith Garcia-Aymerich, K Nishimura, Michael I. Polkey, Miek Hornikx, MR Boland, MR Miller, MT Durheim, Niklas Karlsson, P Lange, PH Quanjer, PW Jones, PW Jones, RA Rabinovich, Roberto A. Rabinovich, S Kim, S Kon, SJ Singh, SK Park, SN Vorrink, T Troosters, T van der Molen, Thierry Troosters, Thys Van der Molen, Willem I. de Boer, Wim Janssens, Yuanpu Peter Di, Zafeiris Louvaris, ZS Depew   +53 more
core   +8 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Global Strategies for Population Management of Domestic Cats (Felis catus): A Systematic Review to Inform Best Practice Management for Remote Indigenous Communities in Australia

Animals, 2020
Pet domestic cat (Felis catus) populations are increasing all around the world, resulting in an increase in contact with humans and wildlife, potentially spreading zoonotic diseases and predating on wildlife.
Brooke P. A. Kennedy, Bonny Cumming, Wendy Y. Brown   +2 more
doaj   +1 more source

Cytological Findings of 140 Bile Samples from Dogs and Cats and Associated Clinical Pathological Data [PDF]

, 2015
BACKGROUND: Cholecystocentesis can be part of the diagnostic workup of hepatobiliary disease in small animals, but literature on cytological evaluation of bile is scant.
Boomkens, Brain, Braun, Center, Clark, Crews, Flatland, Geigy, Kook, Lawrence, Neel, Ramery, Savary-Bataille, Sung, Voros, Wagner, Weiss   +16 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Impact of diversity of Mycoplasma hyopneumoniae strains on lung lesions in slaughter pigs [PDF]

, 2017
The importance of diversity of Mycoplasma hyopneumoniae (M. hyopneumoniae) strains is not yet fully known. This study investigated the genetic diversity of M.
Arsenakis, Ioannis, Boyen, Filip, Del Pozo Sacristán, Rubén, Haesebrouck, Freddy, Maes, Dominiek, Michiels, Annelies, Piepers, Sofie, Vranckx, Katleen   +7 more
core   +2 more sources

Diseases Transmitted by Cats

Microbiology Spectrum, 2015
ABSTRACT Humans and cats have shared a close relationship since ancient times. Millions of cats are kept as household pets, and 34% of households have cats. There are numerous diseases that may be transmitted from cats to humans.
Ellie J C, Goldstein, Fredrick M, Abrahamian   +1 more
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source