Results 11 to 20 of about 265,603 (330)

Amino Acid Catabolism: An Overlooked Area of Metabolism

open access: yesNutrients, 2023
Amino acids have been extensively studied in nutrition, mainly as key elements for maintaining optimal protein synthesis in the body as well as precursors of various nitrogen-containing compounds. However, it is now known that amino acid catabolism is an
Armando R Tovar   +2 more
exaly   +2 more sources

Serine Catabolism Feeds NADH when Respiration Is Impaired

open access: yesCell Metabolism, 2020
Summary: NADH provides electrons for aerobic ATP production. In cells deprived of oxygen or with impaired electron transport chain activity, NADH accumulation can be toxic.
Melanie R McReynolds   +2 more
exaly   +2 more sources

Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

open access: yesCancer Cell, 2017
Summary How tumor-infiltrating T lymphocytes (TILs) adapt to the metabolic constrains within the tumor microenvironment (TME) and to what degree this affects their ability to combat tumor progression remain poorly understood. Using mouse melanoma models,
Gao Zhang   +2 more
exaly   +2 more sources

Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism

open access: yesFrontiers in Physiology, 2021
Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body anabolism and energy homeostasis. They also serve as signaling molecules, for example, being able to activate mammalian/mechanistic target of rapamycin complex 1 (mTORC1).
Gagandeep Mann   +3 more
doaj   +2 more sources

Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism

open access: yesCell Metabolism
Pyruvate and branched-chain amino acid (BCAA) metabolism are pivotal pathways in tumor progression, yet the intricate interplay between them and its implications for tumor progression remain elusive.
Junli Liu, Weiwei Yang, Suzhen Chen
exaly   +2 more sources

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes

open access: yesJournal of Cell Biology, 2019
Lipolysis and lipophagy are thought to be distinct mechanisms for lipid droplet catabolism. In hepatocytes, Schott et al. report that these pathways may operate synergistically: the lipolysis enzyme ATGL targets large LDs upstream of lipophagy, which is ...
Ryan J Schulze   +2 more
exaly   +2 more sources

Amino Acid Catabolism in Plants

open access: yesMolecular Plant, 2015
Tatjana M Hildebrandt   +2 more
exaly   +2 more sources

Metabolic Fate Is Defined by Amino Acid Nature in Gilthead Seabream Fed Different Diet Formulations

open access: yesAnimals, 2022
The sustainability of the Aquaculture industry relies on optimising diets to promote nitrogen retention and maximise fish growth. The aim of this study was to assess how different dietary formulations influence the bioavailability and metabolic fate of ...
Rita Teodósio   +4 more
doaj   +1 more source

The hierarchy of sugar catabolization in Lactococcus cremoris

open access: yesMicrobiology Spectrum, 2023
Bacteria adapt to nutrient availability by regulating the synthesis of enzymes. Transcriptome- and multi-sugar growth studies suggest that Lactococcus cremoris represses genes involved in the catabolization of lower growth rate-supporting (lower quality)
Sieze Douwenga   +8 more
doaj   +1 more source

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