Results 41 to 50 of about 190,565 (312)

Vitamin D and Its Metabolites Status before and during Chemotherapy in Caucasian Breast Cancer Patients

Metabolites, 2023
Background: The predictive role of vitamin D (VD) in breast cancer (BC) patients’ survival is still being investigated. This paper aims to evaluate the changes in VD metabolites during chemotherapy (CTH) and the predictive role of VD status in Caucasian ...
Małgorzata Kimsa-Furdzik, Anna Bednarek, Grzegorz Hibner, Paulina Czajka-Francuz, Sylwia Cisoń-Jurek, Dobromiła Karawasiecka, Bożena Szymczak, Jerzy Wojnar, Jerzy Chudek, Tomasz Francuz   +9 more
doaj   +1 more source

How Leaves Turn Yellow: Catabolism of Chlorophyll

, 2004
This chapter discusses the catabolism of chlorophyll and regulation and significance of chlorophyll breakdown. The green color of chlorophyll (Chl) is due to the conjugated system of π electrons in the tetrapyrrolic macrocycle and, the loss of green ...
P. Matile, S. Hörtensteiner, Hörtensteiner, Stefan, Matile, P.   +3 more
core   +1 more source

Tryptophan catabolism reflects disease activity in human tuberculosis. [PDF]

, 2020
There is limited understanding of the role of host metabolism in the pathophysiology of human tuberculosis (TB). Using high-resolution metabolomics with an unbiased approach to metabolic pathway analysis, we discovered that the tryptophan pathway is ...
Ismail, Nazir Ahmed, Blumberg, Henry M, Brust, James C.M., Blumberg, Henry M., Siddiqa, Amnah, Brust, James Cm, Ismail, Nazir, Shah, N. Sarita, Day, Cheryl L, Nizam, Azhar, Ouma, Samuel G, Gandhi, Neel R, Tukvadze, Nestani, Collins, Jeffrey M, Kempker, Russell R, Kempker, Russell R., Liu, Ken, Collins, Jeffrey M., Ouma, Samuel G., Jones, Dean P., Jones, Dean P, Shah, N Sarita, Rengarajan, Jyothi, Ziegler, Thomas R, Ziegler, Thomas R., Ernst, Joel D., Day, Cheryl L., Ernst, Joel D, Li, Shuzhao, Gandhi, Neel R.   +29 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ethanolamine enhances adhesion, promotes microcompartment formation, and modulates gene expression in Levilactobacillus brevis ATCC 14869

Gut Microbes
Ethanolamine is an abundant compound in the gastrointestinal tract and a valuable source of carbon and nitrogen for pathogenic bacteria harboring ethanolamine utilization (eut) genes.
Polycronis P. Akouris, Gerrit A. Stuivenberg, John A. Chmiel, Wongsakorn Kiattiburut, Annabel Poon, Gregor Reid, Jeremy P. Burton   +6 more
doaj   +1 more source

Resistance of chylomicron and VLDL remnants to post-heparin lipolysis in ApoE-deficient mice: the role of apoE in lipoprotein lipase-mediated lipolysis in vivo and in vitro

Journal of Lipid Research, 1998
The interaction of lipoprotein lipase (LPL) with triglyceride-rich lipoproteins is governed by a number of factors, such as apolipoprotein (apo) C-II. The role of apoE in lipolysis is controversial.
Eva Zsigmond, Yasu Fuke, Lan Li, Kunihisa Kobayashi, Lawrence Chan   +4 more
doaj   +1 more source

Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism

Frontiers in Physiology, 2021
Branched-chain amino acids (BCAAs) are critical for skeletal muscle and whole-body anabolism and energy homeostasis. They also serve as signaling molecules, for example, being able to activate mammalian/mechanistic target of rapamycin complex 1 (mTORC1).
Gagandeep Mann, Stephen Mora, Glory Madu, Olasunkanmi A. J. Adegoke   +3 more
doaj   +1 more source

Pathways for branched chain amino acid catabolism.

, 2016
Valine degradation produces one propionyl-CoA, isoleucine catabolism produces one propionyl-CoA and one acetyl-CoA, and leucine catabolism produces three acetyl-CoA.
Nicholas Marze (841739), Scott B. Crown (841738), Maciek R. Antoniewicz (841740)   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Ethanolamine Utilization in Bacteria

mBio, 2018
Ethanolamine (EA) is a valuable source of carbon and/or nitrogen for bacteria capable of its catabolism. Because it is derived from the membrane phospholipid phosphatidylethanolamine, it is particularly prevalent in the gastrointestinal tract, which is ...
Karan Gautam Kaval, Danielle A. Garsin
doaj   +1 more source