Results 21 to 30 of about 190,565 (312)

Immuno-Modulatory Effects of Intervertebral Disc Cells

Frontiers in Cell and Developmental Biology, 2022
Low back pain is a highly prevalent, chronic, and costly medical condition predominantly triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and biochemical changes in intervertebral discs (IVD) that prompt a pathologic
Paola Bermudez-Lekerika, Paola Bermudez-Lekerika, Katherine B. Crump, Katherine B. Crump, Sofia Tseranidou, Andrea Nüesch, Exarchos Kanelis, Exarchos Kanelis, Ahmad Alminnawi, Ahmad Alminnawi, Laura Baumgartner, Estefano Muñoz-Moya, Roger Compte, Francesco Gualdi, Leonidas G. Alexopoulos, Leonidas G. Alexopoulos, Liesbet Geris, Liesbet Geris, Liesbet Geris, Karin Wuertz-Kozak, Karin Wuertz-Kozak, Christine L. Le Maitre, Jérôme Noailly, Benjamin Gantenbein, Benjamin Gantenbein   +24 more
doaj   +1 more source

EFFECT OF LEVELS OF DIETARY PROTEIN AND ADDITION OF PROBIOTIC (SACCHAROMYCES CEREVISIAE AND BACILLUS SUBTILIS) ON SERUM CONCENTRATIONS OF INSULIN, TSH AND GROWTH HORMONES IN AWASSI LAMBS [PDF]

Al-Qadisiyah Journal For Agriculture Sciences, 2020
To maintain the body on its metabolic activities, including catabolic and anabolic processes, it needs tools. Insulin, thyroxine, growth hormone and other hormones are considered the tools that contribute to regulate metabolism in living organism.
A. F. Al-Abedi, A. A. Saeed, K. S. Al-Huosyney   +2 more
doaj   +1 more source

TArget-Responsive Subcellular Catabolism Analysis for Early-stage Antibody-Drug Conjugates Screening and Assessment

, 2020
Key events including antibody-antigen affinity, ADC internalization, trafficking and lysosomal proteolysis-mediated payload release combinatorially determine the therapeutic efficacy and safety for ADCs.
Guangji, Wang, Jiali, Liu, Xiaofang, Zhang, Fang, Zhou, Yazhong, Liu, Jingwei, Zhang, Hua, Sang, Hui, Ye   +7 more
core   +1 more source

Trafficking pathways of mycolic acids: structures, origin, mechanism of formation, and storage form of mycobacteric acids

Journal of Lipid Research, 2009
Mycolic acids, the hallmark of mycobacteria and related bacteria, are major and specific components of their cell envelope and essential for the mycobacterial survival.
Elie Rafidinarivo, Marie-Antoinette Lanéelle, Henri Montrozier, Pedro Valero-Guillén, José Astola, Marina Luquin, Jean-Claude Promé, Mamadou Daffé   +7 more
doaj   +1 more source

Metabolic profiles of 2-oxindole-3-acetyl-amino acid conjugates differ in various plant species

Frontiers in Plant Science, 2023
Auxins are a group of phytohormones that play a key role in plant growth and development, mainly presented by the major member of the family - indole-3-acetic acid (IAA).
Pavel Hladík, Ivan Petřík, Asta Žukauskaitė, Ondřej Novák, Aleš Pěnčík   +4 more
doaj   +1 more source

Case report: Successful combination therapy with double-filtration plasmapheresis and rituximab under the condition of the use of a sensor-augmented pump for type B insulin resistance syndrome

Frontiers in Endocrinology, 2022
Type B insulin resistance syndrome (TBIR) is a rare disease characterized by refractory diabetes due to severe insulin resistance caused by anti-insulin receptor autoantibodies, and a standard treatment regimen for TBIR has not been established, leading ...
Arata Osanami, Masatoshi Kanda, Tatsuya Sato, Tatsuya Sato, Chikako Akazawa, Shuhei Baba, Hiroaki Komatsu, Kazuyuki Murase, Tomohisa Yamashita, Toshiyuki Yano   +9 more
doaj   +1 more source

Administration of bovine anti-IGF-1 immunoglobulin to dietary protein deficient rats alters dietary intake and plasma IGF-1 binding profiles, but does not affect change in body mass

Animal, 2010
The potential of antibodies raised against insulin-like growth factor-1 (IGF-1) as a treatment to enhance the anabolic actions of IGF-1 has been demonstrated in both rodent and ruminant models. We investigated whether treatment of genetically normal rats
N.N. Smith, M.J. Kelly, J.M. Pell, R.A. Hill   +3 more
doaj   +1 more source

Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803

, 2007
Schriek S, Rückert C, Staiger D, Pistorius EK, Michel K-P. Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis ...
Klaus-Peter Michel, Schriek, Sarah, Staiger Dorothee, Michel, Klaus-Peter, Rückert Christian, Schriek Sarah, Pistorius Elfriede K, Elfriede K Pistorius, Staiger, Dorothee, Sarah Schriek, Rückert, Christian ; https://orcid.org/, Michel Klaus-Peter, Pistorius, Elfriede K., Christian Rückert, Dorothee Staiger   +14 more
core   +1 more source

Lipid catabolism in microalgae [PDF]

New Phytologist, 2018
SummaryLipid degradation processes are important in microalgae because survival and growth of microalgal cells under fluctuating environmental conditions require permanent remodeling or turnover of membrane lipids as well as rapid mobilization of storage lipids.
Fantao Kong, Ismael Torres Romero, Jaruswan Warakanont, Yonghua Li‐Beisson   +3 more
openaire   +3 more sources

The Atg1-Tor Pathway Regulates Yolk Catabolism in Drosophila Embryos

, 2021
Yolk provides an important source of nutrients during the early development of oviparous organisms. It is composed mainly of vitellogenin proteins packed into membrane-bound compartments called yolk platelets.
Mitchison, Timothy, Sopko, Richelle, Kuhn, Hallie, Coughlin, Margaret, Perrimon, Norbert   +4 more
core   +1 more source