Results 61 to 70 of about 190,565 (312)

Auxin catabolism protein families in carnation.

, 2018
Auxin catabolism protein families in carnation.
Ana Belén Sánchez-García (428339), Manuel Acosta (52993), José Manuel Pérez-Pérez (166612), Sergio Ibáñez (5144993), Antonio Cano (103418)   +4 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Thermodynamic Limits and Optimality of Microbial Growth

Entropy, 2020
Understanding microbial growth with the use of mathematical models has a long history that dates back to the pioneering work of Jacques Monod in the 1940s.
Nima P. Saadat, Tim Nies, Yvan Rousset, Oliver Ebenhöh   +3 more
doaj   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Chromosome-Level Genome Assembly and Comparative Transcriptome Analyses Identified Energy Conservation as a Key Strategy for Anadromous Adaptation of the Hilsa Shad, Tenualosa ilisha (Clupeiformes: Dorosomatidae)

Biomolecules
Anadromous migration toward riverine tributaries is often challenged by altered environmental cues, food scarcity, and energy demands, sometimes at the expense of life itself.
Kishor Kumar Sarker, Liang Lu, Roland Nathan Mandal, Md Rashedur Rahman, Anirban Sarker, Mohammad Abdul Baki, Chenhong Li   +6 more
doaj   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Mitigating disuse‐induced skeletal muscle atrophy in ageing: Resistance exercise as a critical countermeasure

Experimental Physiology
The gradual deterioration of physiological systems with ageing makes it difficult to maintain skeletal muscle mass (sarcopenia), at least partly due to the presence of ‘anabolic resistance’, resulting in muscle loss.
James McKendry, Giulia Coletta, Everson A. Nunes, Changhyun Lim, Stuart M. Phillips   +4 more
doaj   +1 more source

Unveiling the crucial roles of abscisic acid in plant physiology: implications for enhancing stress tolerance and productivity

Frontiers in Plant Science
Abscisic acid (ABA), one of the six major plant hormones, plays an essential and irreplaceable role in numerous physiological and biochemical processes during normal plant growth and in response to abiotic stresses.
Weiliang Mo, Xunan Zheng, Qingchi Shi, Xuelai Zhao, Xiaoyu Chen, Zhenming Yang, Zecheng Zuo   +6 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Complex Mechanical Loading and Pro‐Inflammatory Cytokines in Intervertebral Disc Degeneration

JOR Spine
Background Intervertebral disc (IVD) degeneration is a major contributor to low back pain, yet its initiating factors remain unclear. While the individual effects of pro‐inflammatory cytokines and mechanical loading on IVDs have been studied, their ...
Katherine B. Crump, Estefano Muñoz‐Moya, Kim deGraaf, Paola Bermudez‐Lekerika, Nicole Schwendener, Wolf‐Dieter Zech, Christine L. Le Maitre, Jérôme Noailly, Benjamin Gantenbein   +8 more
doaj   +1 more source