Results 61 to 70 of about 265,603 (330)

PROTEIN CATABOLISM IN RAT LIVER NUCLEI.

open access: yes, 1969
PROTEIN CATABOLISM IN RAT LIVER ...
THOMAS HARRISON. CLAUS (7974368)
core   +6 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Loss of BCAA catabolism during carcinogenesis enhances mTORCl activity and promotes tumor development and progression

open access: yesCell Metabolism, 2019
Summary Tumors display profound changes in cellular metabolism, yet how these changes aid the development and growth of tumors is not fully understood.
Russell E. Ericksen   +12 more
semanticscholar   +1 more source

INTRACELLULAR PROTEIN CATABOLISM IN RAT LIVER.

open access: yes, 1969
INTRACELLULAR PROTEIN CATABOLISM IN RAT ...
CHARLES OTTO. BROSTROM (7982270)
core   +4 more sources

SAFETY OF MIXED ARTIFICIAL NUTRITION IN PATIENTS WITH SEVERE MULTISYSTEM CRANIOCEREBRAL TRAUM

open access: yesНеотложная медицинская помощь, 2017
. Early initiation of artificial nutrition is one of the important components of intensive care for those affected with SMCT. The priority is given to enteral nutrition (EN).
A. P. Shakotko   +5 more
doaj   +1 more source

The Influence of Parenteral Energy and Protein Intakes in the First Week on the Growth of Very Low Birth Weight Babies [PDF]

open access: yesIndian Journal of Neonatal Medicine and Research, 2013
Objective: To compare growth of very low birth weight (VLBW) infants given standard total parenteral nutrition (TPN), providing 25kcal/g amino acids, and high calcium TPN, providing 30kcal/g amino acids.
Christopher Geoffrey Alexander Aiken
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Krüppel-like factor 6–mediated loss of BCAA catabolism contributes to kidney injury in mice and humans

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance The kidney proximal tubule is particularly susceptible to acute injury, which results in loss of fatty acid oxidation (FAO), their primary energy source.
S. Piret   +12 more
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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