Results 61 to 70 of about 211,060 (265)

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Epigallocatechin-3-gallate chitosan nanoparticles in an extender improve the antioxidant capacity and post-thawed quality of Kacang goat semen [version 3; peer review: 1 approved, 2 approved with reservations, 2 not approved]

F1000Research
Background and Aim The Kacang goat (Capra hircus) is an indigenous livestock species in Indonesia that is at risk of extinction due to cross-breeding. Artificial insemination (AI) techniques are expected to increase the population of these goats.
Adeyinka Oye Akintunde, Yudit Oktanella, Suherni Susilowati, Tri Wahyu Suprayogi, Imam Mustofa, Djoko Agus Purwanto   +5 more
doaj   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Oxidative stress in the latissimus dorsi muscle of diabetic rats

Brazilian Journal of Medical and Biological Research, 2000
The purpose of the present study was to investigate the effects of experimental diabetes on the oxidant and antioxidant status of latissimus dorsi (LD) muscles of male Wistar rats (220 ± 5 g, N = 11).
K.L.D. De Angelis, I.A. Cestari, J. Barp, P. Dall'Ago, T.G. Fernandes, P.I. Homem de Bittencourt, A. Belló-Klein, A.A. Belló, S. Llesuy, M.C. Irigoyen   +9 more
doaj   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

Advanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen, Huan Liu, Tengyu Liu, Jie Li, Qizhi Luo, Yan Zhang, Shengkun Li, Hu Li   +7 more
wiley   +1 more source

The influence of high Cd2+ concentrations on lipid peroxidation and antioxidant system function of wheat (Triticum aestivum) and rye (Secale cereale) etiolated shoots [PDF]

Journal of Stress Physiology & Biochemistry, 2012
The influence of high Cd2+ concentrations on lipid peroxidation and antioxidant system function of winter wheat (Triticum aestivum) and rye (Secale cereale) etiolated shoots.
Kolesnichenko A.V., Kolesnichenko V.V.
doaj  

Mycobacterium tuberculosis Catalase Inhibits the Formation of Mast Cell Extracellular Traps

Frontiers in Immunology, 2018
Tuberculosis is one of the leading causes of human morbidity and mortality. Mycobacterium tuberculosis (Mtb) employs different strategies to evade and counterattack immune responses persisting for years.
Marcia Campillo-Navarro, Marcia Campillo-Navarro, Kahiry Leyva-Paredes, Luis Donis-Maturano, Gloria M. Rodríguez-López, Rodolfo Soria-Castro, Blanca Estela García-Pérez, Nahum Puebla-Osorio, Stephen E. Ullrich, Stephen E. Ullrich, Julieta Luna-Herrera, Leopoldo Flores-Romo, Héctor Sumano-López, Sonia M. Pérez-Tapia, Sonia M. Pérez-Tapia, Sergio Estrada-Parra, Iris Estrada-García, Rommel Chacón-Salinas, Rommel Chacón-Salinas   +18 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Effect of nanoporous membranes thickness in electrochemical biosensing performance: application for the detection of a wound infection biomarker

Frontiers in Bioengineering and Biotechnology
Introduction: Nanoporous alumina membranes present a honeycomb-like structure characterized by two main parameters involved in their performance in electrochemical immunosening: pore diameter and pore thickness.
C. Toyos-Rodríguez, C. Toyos-Rodríguez, D. Valero-Calvo, D. Valero-Calvo, A. Iglesias-Mayor, A. Iglesias-Mayor, A. de la Escosura-Muñiz, A. de la Escosura-Muñiz   +7 more
doaj   +1 more source