Results 51 to 60 of about 221,645 (319)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A Technique to Derive Improved Proper Motions for Kepler Objects of Interest [PDF]

open access: yes, 2014
We outline an approach yielding proper motions with higher precision than exists in present catalogs for a sample of stars in the Kepler field. To increase proper motion precision we combine first moment centroids of Kepler pixel data from a single ...
Benedict, G. Fritz   +3 more
core   +4 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Determination of Abundances of Chemical Elements in Open Star Clusters of the Galaxy

open access: yesOpen Astronomy, 2016
Spectroscopic determinations of the relative abundances of chemical elements produced in different nuclear-synthesis processes, [el/Fe], are collected for 90 open star clusters of the Galaxy using data from 109 papers published between 1991 and 2015 ...
Gozha M. L.   +2 more
doaj   +1 more source

Revised Catalog of GALEX Ultraviolet Sources. I. The All-sky Survey: GUVcat_AIS

open access: yes, 2017
The Galaxy Evolution Explorer (GALEX) imaged the sky in two Ultraviolet (UV) bands, far-UV (FUV) and near-UV (NUV), delivering the first comprehensive sky surveys at these wavelengths.
Bianchi, Luciana   +2 more
core   +1 more source

A digital catalog of high‐density markers for banana germplasm collections [PDF]

open access: gold, 2021
Mathieu Rouard   +7 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Astronomical Surveys and Big Data

open access: yesOpen Astronomy, 2016
Recent all-sky and large-area astronomical surveys and their catalogued data over the whole range of electromagnetic spectrum, from γ-rays to radio waves, are reviewed, including such as Fermi-GLAST and INTEGRAL in γ-ray, ROSAT, XMM and Chandra in X-ray,
Mickaelian Areg M.
doaj   +1 more source

The WISE AGN Catalog [PDF]

open access: yes, 2017
We present two large catalogs of AGN candidates identified across ~75% of the sky from the Wide-field Infrared Survey Explorer's AllWISE Data Release. Both catalogs, some of the largest such catalogs published to date, are selected purely on the basis of
Assef, R. J.   +5 more
core   +3 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

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