Results 111 to 120 of about 464,312 (316)

Synthesis and Catalysis

CHIMIA, 2010
Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts
Gademann, K., Pfaltz, A., Wegner, H. A., Wennemers, H., Woggon, W. -D., Chougnet, A.   +5 more
openaire   +5 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Sustainable Catalysis for Green Chemistry and Energy Transition

Catalysis sits at the heart of sustainable development, and plays an instrumental role in addressing modern environmental challenges [...
Wajid Zaman, Muhammad Saeed Akhtar
core   +1 more source

Enzyme-Catalysis

, 2019
As a pioneer of the enzymes manufacturer industry, Creative Enzymes is known as its specialization and consolidates its leader's position in this field gradually since the year founded by always taking initiative in this field.
Iva Colter (6713138)
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future Directions

, 2015
Em enviat el pdf de l'article, pero disposem tant del preprint com el postprint.Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future ...
Jan-E. Bäckvall, PAMIES OLLÉ, OSCAR, Pàmies, Oscar, Bäckvall, Jan-E.,, Diéguez, Montserrat, DIÉGUEZ FERNÁNDEZ, MONTSERRAT   +5 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

How the Chemical Properties of Polysaccharides Make It Possible to Design Various Types of Organic–Inorganic Composites for Catalytic Applications

Molecules
Recently, the use of plant-origin materials has become especially important due to the aggravation of environmental problems and the shortage and high cost of synthetic materials.
Sandugash Akhmetova, Alima Zharmagambetova, Eldar Talgatov, Assemgul Auyezkhanova, Makpal Malgazhdarova, Murat Zhurinov, Arlan Abilmagzhanov, Aigul Jumekeyeva, Alima Kenzheyeva   +8 more
doaj   +1 more source

Nitrogen Doped Carbon Nanotubes and Nanofibers for Green Hydrogen Production: Similarities in the Nature of Nitrogen Species, Metal–Nitrogen Interaction, and Catalytic Properties

Energies, 2019
The effect of nitrogen doped bamboo-like carbon nanotubes (N−CNTs) on the properties of supported platinum (0.2 and 1 wt %) catalysts in formic acid decomposition for hydrogen production was studied.
Olga Podyacheva, Alexander Lisitsyn, Lidiya Kibis, Andrei Boronin, Olga Stonkus, Vladimir Zaikovskii, Arina Suboch, Vladimir Sobolev, Valentin Parmon   +8 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source