Results 91 to 100 of about 398,278 (315)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

On the origin of the cobalt particle size effects in Fischer−Tropsch catalysis

, 2009
The effects of metal particle size in catalysis are of prime scientific and industrial importance and call for a better understanding. In this paper the origin of the cobalt particle size effects in Fischer−Tropsch (FT) catalysis was studied.
Inorganic Chemistry and Catalysis, Sub Inorganic Chemistry and Catalysis, den Breejen, J.P., de Jong, K.P., Froseth, V., Holmen, A., Radstake, P.B., Bezemer, G.L., Bitter, J.H., Dep Scheikunde   +9 more
core  

Structural Changes of Mo/ZSM-5 Catalysts During the Methane Dehydroaromatization

Eurasian Chemico-Technological Journal, 2010
The structure changes of Mo/ZSM-5 catalysts with different Mo content (2 and 10 wt. % Mo) and Si/Al atomic ratio (17, 30 and 45) during the methane dehydroaromatization have been investigated by X-ray powder diffractometry, N2 adsorption and ...
Z. R. Ismagilov, E. V. Matus, I. Z. Ismagilov, M. A. Kerzhentsev, V. I. Zaikovskii, K. D. Dosumov, A. G. Mustafin   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Tuning graphitic oxide for initiator- and metal-free aerobic epoxidation of linear alkenes

Nature Communications, 2016
Graphitic oxide is readily produced by the oxidation of graphite. Here the authors show that the amount and nature of the oxidant can be used to tune the properties of graphitic oxide, and furthermore report a carbocatalyst for alkene epoxidation without
Samuel Pattisson, Ewa Nowicka, Upendra N. Gupta, Greg Shaw, Robert L. Jenkins, David J. Morgan, David W. Knight, Graham J. Hutchings   +7 more
doaj   +1 more source

Ligand engineering to achieve enhanced ratiometric oxygen sensing in a silver cluster-based metal-organic framework

Nature Communications, 2020
Incorporating dual fluorescence and phosphorescence into a single matrix is attractive for oxygen sensing, but material design is challenging. Here the authors achieve dual fluorescence-phosphorescence from a single linker chromophore in a silver ...
Xi-Yan Dong, Yubing Si, Jin-Sen Yang, Chong Zhang, Zhen Han, Peng Luo, Zhao-Yang Wang, Shuang-Quan Zang, Thomas C. W. Mak   +8 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Development of Tip-enhanced Raman Spectroscopy and its Application to Heterogeneous Catalysis Research

, 2018
Catalysis is at the forefront of many developments to make our society more sustainable and less dependent on fossil resources, such as coal, gas and crude oil.
Kumar, Naresh, Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis   +2 more
core  

Reactivity Descriptor in Solid Acid Catalysis: Predicting Turnover Frequencies for Propene Methylation in Zeotypes

, 2014
Recent work has reported the discovery of metal surface catalysts by employing a descriptor-based approach, establishing a correlation between a few well-defined properties of a material and its catalytic activity.
Studt, Felix, Inorganic Chemistry and Catalysis, Sub Inorganic Chemistry and Catalysis, Bert M. Weckhuysen, Brogaard, Rasmus Y., Weckhuysen, Bert M., Felix Studt, Chuan-Ming Wang, Rasmus Y. Brogaard, Jens K. Nørskov, Nørskov, Jens K., Wang, Chuan Ming   +11 more
core   +1 more source

Methane dry reforming over Ni catalysts supported on Ce–Zr oxides prepared by a route involving supercritical fluids

Open Chemistry, 2017
Ce0.5Zr0.5O2 mixed oxides were prepared in a flow reactor in supercritical isopropanol with acetylacetone as a complexing agent. Variation of the nature of the Zr salt and the temperature of synthesis affected the phase composition, morphology and ...
Smirnova Marina Yu., Bobin Aleksei S., Pavlova Svetlana N., Ishchenko Arcady V., Selivanova Aleksandra V., Kaichev Vasilii V., Cherepanova Svetlana V., Krieger Tamara A., Arapova Marina V., Roger Anne-Cecile, Adamski Andrzej, Sadykov Vladislav A.   +11 more
doaj   +1 more source