Results 81 to 90 of about 464,312 (316)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The use of energy from alternative energy sources as well as the use of waste heat are key elements of an efficient energetics. Adsorption heat storage is a technology that allows solving such problems.
Alexandra Grekova +3 more
doaj +1 more source
Toward innovative photothermal catalysis
This chapter introduces gas-solid heterogeneous photothermal catalysis as a novel approach for advancing the field of heterogeneous catalysis. It begins by explaining the fundamental insights into charge carriers and heat generation under light and their
Amal, Rose +2 more
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Chiral N-heterocyclic Carbene Gold Complexes: Synthesis and Applications in Catalysis
N-Heterocyclic carbenes have found many applications in modern metal catalysis, due to the formation of stable metal complexes, and organocatalysis. Among a myriad of N-heterocyclic carbene metal complexes, gold complexes have gained a lot of attention ...
Michalak, Kośnik
core +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Abstract This review is concerned with nanoscale carbon as a catalyst. Elemental carbon has become available in many nanostructured forms representing combinations of the hybridizations found in fundamental carbon allotropes, and the materials can be enriched by a large number of surface functional groups, some generated by nanostructuring ...
openaire +2 more sources
Due to the increasing emission of carbon dioxide (CO2), greenhouse effects are becoming more and more severe, causing global climate change. The conversion and utilization of CO2 is one of the possible solutions to reduce CO2 concentrations.
Liu, Miao +9 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

