Results 61 to 70 of about 398,278 (315)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Engineering and Sizing Nanoreactors To Confine Metal Complexes for Enhanced Catalytic Performance

, 2014
Homogeneous metal complexes often display superior activity and selectivity in catalysis of chemical transformations. Heterogenization of these complexes by immobilization on solid supports has been used to facilitate recovery, but this is often ...
Klein Gebbink, Bert, Inorganic Chemistry and Catalysis, Sub Inorganic Chemistry and Catalysis, de Jongh, Petra E., Prieto Gonzalez, Gonzalo, de Jong, Krijn P., Organic Chemistry and Catalysis, Yazerski, Vital, Roiban, Lucian, Shakeri, Mozaffar, Sub Organic Chemistry and Catalysis   +10 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Surface- and Tip-Enhanced Raman Spectroscopy in Catalysis [PDF]

, 2016
Surface- and tip-enhanced Raman spectroscopy (SERS and TERS) techniques exhibit highly localized chemical sensitivity, making them ideal for studying chemical reactions, including processes at catalytic surfaces.
Kumar, Naresh, Thomas Hartman, Bert M. Weckhuysen, Hartman, Thomas, van den Berg, Albert; id_orcid, Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis, Naresh Kumar, Wondergem, Caterina S., Caterina S. Wondergem, Albert van den Berg, Weckhuysen, Bert M., van den Berg, Albert   +12 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Meet the Women of Catalysis [PDF]

, 2019
ChemCatChem celebrates the achievements of female-led research groups in the field of catalysis. With this initiative, we seek to highlight the breadth and depth of the best research developed by women, and to increase its visibility in the wider ...
de Jongh, Petra E., Fogg, Deryn E., Wu, Li Zhu, González-Gallardo, Sandra   +3 more
core  

Isostearic Acid: A Unique Fatty Acid with Great Potential [PDF]

, 2016
Vegetable oils and animal fats are important and established raw materials for the production of chemicals and ingredients. From its origins more than 150 years ago, the oleochemical industry has grown in scale and diversity to become an important branch
Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis, Bruijnincx, P.C.A., Wiedemann, S.C.C., Weckhuysen, B.M.   +4 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cobalt particle size effects in catalysis

, 2010
Aim of the work described in this thesis was first to investigate cobalt particle size effects in heterogeneous catalysis. The main focus was to provide a deeper understanding of the origin of the cobalt particle size effects in Fischer-Tropsch (FT ...
Inorganic Chemistry and Catalysis, Sub Inorganic Chemistry and Catalysis, den Breejen, J.P.   +2 more
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