Results 61 to 70 of about 214,928 (247)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The thermophysical properties of a promising composite adsorbent based on multi-wall carbon nanotubes for heat storage

Materials for Renewable and Sustainable Energy
The use of energy from alternative energy sources as well as the use of waste heat are key elements of an efficient energetics. Adsorption heat storage is a technology that allows solving such problems.
Alexandra Grekova, Svetlana Strelova, Marina Solovyeva, Mikhail Tokarev   +3 more
doaj   +1 more source

Tuning graphitic oxide for initiator- and metal-free aerobic epoxidation of linear alkenes

Nature Communications, 2016
Graphitic oxide is readily produced by the oxidation of graphite. Here the authors show that the amount and nature of the oxidant can be used to tune the properties of graphitic oxide, and furthermore report a carbocatalyst for alkene epoxidation without
Samuel Pattisson, Ewa Nowicka, Upendra N. Gupta, Greg Shaw, Robert L. Jenkins, David J. Morgan, David W. Knight, Graham J. Hutchings   +7 more
doaj   +1 more source

Ligand engineering to achieve enhanced ratiometric oxygen sensing in a silver cluster-based metal-organic framework

Nature Communications, 2020
Incorporating dual fluorescence and phosphorescence into a single matrix is attractive for oxygen sensing, but material design is challenging. Here the authors achieve dual fluorescence-phosphorescence from a single linker chromophore in a silver ...
Xi-Yan Dong, Yubing Si, Jin-Sen Yang, Chong Zhang, Zhen Han, Peng Luo, Zhao-Yang Wang, Shuang-Quan Zang, Thomas C. W. Mak   +8 more
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Catalysis Science in China: From Traditional Techniques to Modern Innovations

Natural Sciences
As a recipient and learner of modern sciences, China has made significant strides in catalysis research and application over the past century and a half.
Zhiliang Li, Xianbiao Fu
doaj   +1 more source

Evaluation of particle size effect on two-phase flow distribution in a hydrotreatment reactor guard bed using particle-resolved CFD simulations

Chimica Techno Acta
Trickle bed reactors with solid catalyst pellets are important and widely used large-scale apparatuses in the chemical and oil refining industries. In order to reduce the effects of poisons on the catalyst bed and to extend the catalyst loading service ...
Ivan A. Mik, Oleg P. Klenov, Ivan S. Golubev, Pavel P. Dik, Sergey I. Reshetnikov, Alexandr S. Noskov   +5 more
doaj   +1 more source

Structural Changes of Mo/ZSM-5 Catalysts During the Methane Dehydroaromatization

Eurasian Chemico-Technological Journal, 2010
The structure changes of Mo/ZSM-5 catalysts with different Mo content (2 and 10 wt. % Mo) and Si/Al atomic ratio (17, 30 and 45) during the methane dehydroaromatization have been investigated by X-ray powder diffractometry, N2 adsorption and transmission
Z. R. Ismagilov, E. V. Matus, I. Z. Ismagilov, M. A. Kerzhentsev, V. I. Zaikovskii, K. D. Dosumov, A. G. Mustafin   +6 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source