Results 61 to 70 of about 726,049 (330)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Application of Sonotriboluminescence to Determine Arene Molecules in Hydrocarbons

open access: yesMolecules, 2023
The sonotriboluminescence of suspensions of terbium(III) and europium(III) sulfates in decane without and in the presence of benzene, toluene and p-xylene was studied.
Adis A. Tukhbatullin   +6 more
doaj   +1 more source

Inverse magnetic catalysis induced by sphalerons

open access: yes, 2013
The recently discovered inverse magnetic catalysis around the critical temperature indicates that some important information is missing in our current understanding of conventional chiral dynamics of QCD, which is enhanced by the magnetic field.
Chao, Jingyi, Chu, Pengcheng, Huang, Mei
core   +1 more source

Kinetics of catalysis with surface disorder [PDF]

open access: yes, 1996
We study the effects of generalised surface disorder on the monomer-monomer model of heterogeneous catalysis, where disorder is implemented by allowing different adsorption rates for each lattice site.
D. A. Head   +13 more
core   +2 more sources

RNA catalysis

open access: yesCurrent Opinion in Structural Biology, 1998
Our understanding of the relationship between the structure of RNA and its catalytic activity has advanced significantly in the past year. These advances include time-resolved crystallographic studies on the hammerhead ribozyme, as well as new structures of a group I intron, a lead(II)-cleavage ribozyme, a hepatitis delta virus ribozyme, and components
openaire   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Magnetic Catalysis in AdS4

open access: yes, 2012
We study the formation of fermion condensates in Anti de Sitter space. In particular, we describe a novel version of magnetic catalysis that arises for fermions in asymptotically AdS4 geometries which cap off in the infra-red with a hard wall.
Albash T   +19 more
core   +1 more source

Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools. [PDF]

open access: yes, 2016
This review discusses the use of molecular modeling tools, together with existing experimental findings, to provide a complete atomic-level description of enzyme dynamics and function.
Chang, Chia-En A   +3 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Catalysis of the electrochemical reduction of oxygen by bacteria isolated from electro-active biofilms formed in seawater [PDF]

open access: yes, 2011
Biofilmsformed in aerobic seawater on stainless steel are known to be efficient catalysts of the electrochemicalreduction of oxygen. Based on their genomic analysis, seven bacterial isolates were selected and a cyclic voltammetry (CV) procedure was ...
Bergel, Alain   +7 more
core   +2 more sources

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