Results 161 to 170 of about 4,561,775 (254)

Gain-of-function mutations in the catalytic domain of DOT1L promote lung cancer malignant phenotypes via the MAPK/ERK signaling pathway. [PDF]

Sci Adv, 2023
Zhang J, Yang T, Han M, Wang X, Yang W, Guo N, Ren Y, Cui W, Li S, Zhao Y, Zhai X, Jia L, Yang J, Wu C, Wang L.   +14 more
europepmc   +1 more source

Structural basis for the pathogenicity of parkin catalytic domain mutants. [PDF]

J Biol Chem
Wagner JP, Sauvé V, Saran A, Gehring K.
europepmc   +1 more source

Comprehensive In Silico Functional Prediction Analysis of CDKL5 by Single Amino Acid Substitution in the Catalytic Domain. [PDF]

Int J Mol Sci, 2022
Yoshimura Y, Morii A, Fujino Y, Nagase M, Kitano A, Ueno S, Takeuchi K, Yamashita R, Inazu T.   +8 more
europepmc   +1 more source

Biochemical characterization and X-ray structural and mutagenic analyses of the putative autolysin CdCwlT33800 catalytic domain from <i>Clostridioides difficile</i>. [PDF]

Appl Environ Microbiol
Sekiya H, Nonaka Y, Kamitori S, Tamai E.
europepmc   +1 more source

Structural and functional characterization of the catalytic domain of a cell-wall anchored bacterial lytic polysaccharide monooxygenase from Streptomyces coelicolor. [PDF]

Sci Rep, 2023
Votvik AK, Røhr ÅK, Bissaro B, Stepnov AA, Sørlie M, Eijsink VGH, Forsberg Z.   +6 more
europepmc   +1 more source

Regulation of H3K4me3 breadth and MYC expression by the SETD1B catalytic domain in MLL-rearranged leukemia. [PDF]

Leukemia
Izumi S, Ohtani K, Matsumoto M, Shibata S, Rahmutulla B, Fukuyo M, Nishimoto M, Miyagawa H, Sakaida E, Yokote K, Kitabayashi I, Araki K, Kaneda A, Hoshii T.   +13 more
europepmc   +1 more source

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. [PDF]

Sci Adv, 2022
Ravichandran M, Rafalski D, Davies CI, Ortega-Recalde O, Nan X, Glanfield CR, Kotter A, Misztal K, Wang AH, Wojciechowski M, Rażew M, Mayyas IM, Kardailsky O, Schwartz U, Zembrzycki K, Morison IM, Helm M, Weichenhan D, Jurkowska RZ, Krueger F, Plass C, Zacharias M, Bochtler M, Hore TA, Jurkowski TP.   +24 more
europepmc   +1 more source

Allosteric Communication of the Dimerization and the Catalytic Domain in Photoreceptor Guanylate Cyclase. [PDF]

Biochemistry
Shahu MK, Schuhmann F, Wong SY, Solov'yov IA, Koch KW.   +4 more
europepmc   +1 more source

Axonal Polyneuropathy in 2 Brothers With a Homozygous Missense Variant in the First Catalytic Domain of PCYT2. [PDF]

Neurol Genet, 2022
Leonardis L, Skrjanec Pusenjak M, Maver A, Jaklic H, Ozura Brecko A, Koritnik B, Peterlin B, Writzl K.   +7 more
europepmc   +1 more source

A Soluble Expression Construct of the Isolated Catalytic Domain of Plasmodium falciparum ATP4 Exhibits ATPase Activity Independent of a γ-Phosphate Receiving Aspartate. [PDF]

Mol Microbiol
Beyer T, Caliebe J, Kähler L, Beitz E.
europepmc   +1 more source