Results 11 to 20 of about 10,401,391 (311)
New Catalytic Residues and Catalytic Mechanism of the RNase T1 Family
ACS Bio & Med Chem AuThe ribonuclease T1 family, including RNase Po1 secreted by Pleurotus ostreatus, exhibits antitumor activity. Here, we resolved the Po1/guanosine-3'-monophosphate complex (3'GMP) structure at 1.75 Å. Structure comparison and fragment molecular orbital (FMO) calculation between the apo form and the Po1/3'GMP complex identified Phe38, Phe40, and Glu42 as
Katsuki Takebe +9 more
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Molecular insights of nanozymes from design to catalytic mechanism
Science China Chemistry, 2023 Emerging as cost-effective potential alternatives to natural enzymes, nanozymes have attracted increasing interest in broad fields. To exploit the in-depth potential of nanozymes, rational structural engineering and explicit catalytic mechanisms at the ...
Yuan Xu +8 more
semanticscholar +1 more source
The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family
Nature Communications, 2023 RBR E3 ubiquitin ligases utilise a 2-step catalytic mechanism previously defined for only few of the RBR family members. Here, the authors examine the poorly studied RBRs HOIL-1 and RNF216 to define general principles of RBR catalysis and regulation and ...
Xiangyi S. Wang +6 more
semanticscholar +1 more source
eLife, 2020 Synaptojanin1 (Synj1) is a phosphoinositide phosphatase, important in clathrin uncoating during endocytosis of presynaptic vesicles. It was identified as a potential drug target for Alzheimer’s disease, Down syndrome, and TBC1D24-associated epilepsy ...
Jone Paesmans +10 more
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Advanced Science, 2021 Shifting electrochemical oxygen reduction reaction (ORR) via two‐electron pathway becomes increasingly crucial as an alternative/green method for hydrogen peroxide (H2O2) generation. Here, the development of 2e− ORR catalysts in recent years is reviewed,
Nan Wang +4 more
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Catalysts, 2023 The slow hydrogenation/dehydrogenation kinetics and high thermodynamic stability of the Mg–H bond are the two major limitations for the large-scale utilization of MgH2.
Jinzhe Lyu +4 more
semanticscholar +1 more source
Glucose-oxidase like catalytic mechanism of noble metal nanozymes
Nature Communications, 2021 Au nanoparticles (NPs) have been found to be excellent glucose oxidase mimics, while the catalytic processes have rarely been studied. Here, we reveal that the process of glucose oxidation catalyzed by Au NPs is as the same as that of natural glucose ...
Jinxing Chen +7 more
semanticscholar +1 more source
Catalytic mechanism for Renilla-type luciferases
Nature Catalysis, 2023 The widely used coelenterazine-powered Renilla luciferase was discovered over 40 years ago, but the oxidative mechanism by which it generates blue photons remains unclear.
A. Schenkmayerova +14 more
semanticscholar +1 more source
The Catalytic Mechanism of Carbonic Anhydrase [PDF]
Proceedings of the National Academy of Sciences, 1973 It is shown that an “inverse” relationship between the pH dependencies of the rates of hydration of CO 2 and dehydration of HCO 3 - by carbonic anhydrase (EC 4.2.1.1) is a direct consequence of the thermodynamic equilibrium between ...
S, Lindskog, J E, Coleman
openaire +2 more sources
CO2 reduction into formic acid under hydrothermal conditions: A mini review
Energy Science & Engineering, 2022 Converting CO2, a major component of greenhouse gas in the atmosphere, into value‐added fine chemicals is beneficial from environmental and economic aspects.
Xu Liu +4 more
doaj +1 more source