Results 41 to 50 of about 850,147 (309)
The Catalytic Mechanism of Carbonic Anhydrase [PDF]
Proceedings of the National Academy of Sciences, 1973 It is shown that an “inverse” relationship between the pH dependencies of the rates of hydration of CO 2 and dehydration of HCO 3 - by carbonic anhydrase (EC 4.2.1.1) is a direct consequence of the thermodynamic equilibrium between CO 2 and HCO ...
S, Lindskog, J E, Coleman
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes
Molecules, 2017 Fourteen well-defined ribozyme classes have been identified to date, among which nine are site-specific self-cleaving ribozymes. Very recently, small self-cleaving ribozymes have attracted renewed interest in their structure, biochemistry, and biological
Ki-Young Lee, Bong-Jin Lee
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Frontiers in Chemistry, 2020 The reverse water-gas shift reaction (RWGSR), a crucial stage in the conversion of abundant CO2 into chemicals or hydrocarbon fuels, has attracted extensive attention as a renewable system to synthesize fuels by non-traditional routes.
Xiaodong Chen +9 more
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Mechanistic insights into the key marine dimethylsulfoniopropionate synthesis enzyme DsyB/DSYB
mLife, 2022 Marine algae and bacteria produce approximately eight billion tonnes of the organosulfur molecule dimethylsulfoniopropionate (DMSP) in Earth's surface oceans annually.
Chun‐Yang Li +13 more
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Unraveling the Catalytic Mechanism of Nitrile Hydratases [PDF]
, 2007 To elucidate a detailed catalytic mechanism for nitrile hydratases (NHases), the pH and temperature dependence of the kinetic constants kcat and Km for the cobalt-type NHase from Pseudonocardia thermophila JCM 3095 (PtNHase) were examined.
Holz, Richard C., Mitra, Sanghamitra
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The catalytic mechanism of sulfoxide synthases
Current Opinion in Chemical Biology, 2020 Sulfoxide synthases are non-heme iron enzymes that catalyze oxidative carbonsulfur bond formation in the biosynthesis of thiohistidines such as ergothioneine and ovothiol. The catalytic mechanism of these enzymes has been studied by protein crystallography, steady-state kinetics, non-natural amino acid incorporation and computational modeling.
Anja R. Stampfli, Florian P. Seebeck
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Advanced ScienceIn order to deal with the global energy crisis and environmental problems, reducing carbon dioxide through artificial photosynthesis has become a hot topic.
Bo Gao +11 more
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The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases [PDF]
, 2002 The protein SpoIVB plays a key role in signaling in the sigma (K) checkpoint of Bacillus subtilis. This regulatory mechanism coordinates late gene expression during development in this organism and we have recently shown SpoIVB to be a serine peptidase ...
Brannigan, J A, Cutting, S M, Hoa, N T
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