Results 21 to 30 of about 433,280 (265)

The Catalytic Mechanism of Cdc25A Phosphatase [PDF]

Journal of Biological Chemistry, 2002
Cdc25 phosphatases are dual specificity phosphatases that dephosphorylate and activate cyclin-dependent kinases (CDKs), thereby effecting the progression from one phase of the cell cycle to the next. Despite its central role in the cell cycle, relatively little is known about the catalytic mechanism of Cdc25.
McCain, D. F., Catrina, I. E., Hengge, Alvan C., Zhang, Z. Y.   +3 more
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Selective Catalytic Oxidation of Benzyl Alcohol to Benzaldehyde by Nitrates

Frontiers in Chemistry, 2020
In this paper, ferric nitrate was used to oxidize benzyl alcohol in a mild condition and demonstrated its better performance compared to HNO3. In the reaction, the conversion rate and product selectivity could be both as high as 95% in N2 atmosphere ...
Shurui Xu, Jie Wu, Peng Huang, Chunwen Lao, Hanchao Lai, Yuxiong Wang, Zhenyu Wang, Guoyu Zhong, Xiaobo Fu, Xiaobo Fu, Feng Peng   +10 more
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Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082

Marine Drugs, 2022
Fucoidans represent a type of polyanionic fucose-containing sulfated polysaccharides (FCSPs) that are cleaved by fucoidan-degrading enzymes, producing low-molecular-weight fucoidans with multiple biological activities suitable for pharmacological use ...
Juanjuan Wang, Zebin Liu, Xiaowei Pan, Ning Wang, Legong Li, Yuguang Du, Jianjun Li, Mei Li   +7 more
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The catalytic mechanism of sulfoxide synthases

Current Opinion in Chemical Biology, 2020
Sulfoxide synthases are non-heme iron enzymes that catalyze oxidative carbonsulfur bond formation in the biosynthesis of thiohistidines such as ergothioneine and ovothiol. The catalytic mechanism of these enzymes has been studied by protein crystallography, steady-state kinetics, non-natural amino acid incorporation and computational modeling.
Anja R. Stampfli, Florian P. Seebeck
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Representing Catalytic Mechanisms with Rule Composition

Journal of Chemical Information and Modeling, 2022
Preprint
Jakob L. Andersen, Rolf Fagerberg, Christoph Flamm, Walter Fontana, Juraj Kolcák, Christophe V. F. P. Laurent, Daniel Merkle, Nikolai Nøjgaard   +7 more
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Activation of peroxymonosulfate by CuCo2O4 nano-particles towards long-lasting removal of atrazine

Water Reuse, 2021
The effect of peroxymonosulfate (PMS) activated by nanocrystalline CuCo2O4 (NPS) on removal of atrazine (ATZ) was studied. First, the main experimental parameters were studied, including CuCo2O4 dose, PMS dose, initial pH value, and co-existing ion.
Haoxiang Yin, Jun Li, Haoding Yan, Hanying Cai, Yanjian Wan, Gang Yao, Yong Guo, Bo Lai   +7 more
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The catalytic mechanism of galactose mutarotase [PDF]

Protein Science, 2003
AbstractGalactose mutarotase catalyzes the first step in normal galactose metabolism by catalyzing the conversion of β‐d‐galactose to α‐d‐galactose. The structure of the enzyme from Lactococcus lactis was recently solved in this laboratory and shown to be topologically similar to domain 5 of β‐galactosidase. From this initial X‐ray analysis, four amino
James B, Thoden, Jungwook, Kim, Frank M, Raushel, Hazel M, Holden   +3 more
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Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase

Biochemistry, 2023
Intracellular leucine aminopeptidases (PepA) are metalloproteases from the family M17. These enzymes catalyze peptide bond cleavage, removing N-terminal residues from peptide and protein substrates, with consequences for protein homeostasis and quality control. While general mechanistic studies using model substrates have been conducted on PepA enzymes
Martha Clementine Simpson, Christopher John Harding, Ricardo Melo Czekster, Laura Remmel, Bela E. Bode, Clarissa Melo Czekster   +5 more
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The catalytic mechanism of aspartic proteinases [PDF]

FEBS Letters, 1987
The highly symmetric active site of an aspartic proteinase, endothiapepsin, binds a water molecule ideally situated for nucleophilic attack on a substrate peptide bond whose distortion from planarity is stabilised by interactions of the substrate with the extended binding cleft.
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On the Catalytic Mechanism of Choline Oxidase

Journal of the American Chemical Society, 2005
Choline oxidase catalyzes the four-electron oxidation of choline to glycine betaine, with betaine aldehyde as an intermediate. In this study, primary deuterium and solvent kinetic isotope effects have been used to elucidate the mechanism for substrate oxidation by choline oxidase using both steady-state kinetics and rapid kinetics techniques.
Fan, Fan, Giovanni, Gadda
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