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Practical Neurology, 2018
Remarkably and almost invariably, the clinical phenomenon of cataplexy results from the loss of around 40 000 hypocretin-containing neurones in the lateral hypothalamus in the context of narcolepsy type 1. Cataplexy reflects the dysregulation of rapid-eye-movement (REM) sleep, such that REM-sleep atonia intrudes inappropriately into wakefulness as ...
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Remarkably and almost invariably, the clinical phenomenon of cataplexy results from the loss of around 40 000 hypocretin-containing neurones in the lateral hypothalamus in the context of narcolepsy type 1. Cataplexy reflects the dysregulation of rapid-eye-movement (REM) sleep, such that REM-sleep atonia intrudes inappropriately into wakefulness as ...
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2011
Abstract The term “narcolepsy” was first coined by Gelineau in 1880 with the complete description of a patient with excessive daytime sleepiness (EDS), sleep attacks, and episodes of muscle weakness triggered by emotions. In the current international classification, narcolepsy is characterized by “excessive daytime sleepiness that is typically ...
Seiji, Nishino, Emmanuel, Mignot
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Abstract The term “narcolepsy” was first coined by Gelineau in 1880 with the complete description of a patient with excessive daytime sleepiness (EDS), sleep attacks, and episodes of muscle weakness triggered by emotions. In the current international classification, narcolepsy is characterized by “excessive daytime sleepiness that is typically ...
Seiji, Nishino, Emmanuel, Mignot
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Archives of Sexual Behavior, 1977
Ten married women with cataplexy were found to be rarely orgasmic. Cataplexy is characterized by recurrent episodes of short-lived generalized muscle paralysis. It is precipitated by arousing emotional precipitants such as laughter, fear, and anger. Patients learn to avoid situations exposing them to these precipitants.
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Ten married women with cataplexy were found to be rarely orgasmic. Cataplexy is characterized by recurrent episodes of short-lived generalized muscle paralysis. It is precipitated by arousing emotional precipitants such as laughter, fear, and anger. Patients learn to avoid situations exposing them to these precipitants.
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An Etiology of Narcolepsy-Cataplexy and a Proposed Cataplexy Neuromechanism
International Journal of Neuroscience, 1981Narcolepsy-cataplexy is an idiopathic sleep disorder that reflects a complex neuropathology. Surveys and physiological investigations indicate that genetic and stress factors are involved in its onset and that stress is associated with symptomatic fluctuations and exacerbations of its clinical course.
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Treatment of Cataplexy With Clomipramine
Archives of Neurology, 1975A new antodepressant drug, clomipramine hydrochloride, closely related to imipramine hydrochloride, was used to treat four patients suffering from cataplexy, sleep paralysis, and hypnagogic hallucinations. Attacks of cataplexy were associated with rapid-eye-movement (REM) electroencephalographic patterns.
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Pharmacotherapy options for cataplexy
Expert Opinion on Pharmacotherapy, 2013Narcolepsy with cataplexy is a rare disabling sleep disorder characterized by two major symptoms: excessive daytime sleepiness and cataplexy characterized by a sudden bilateral loss of voluntary muscular tone triggered by strong positive emotional factors.
Régis, Lopez, Yves, Dauvilliers
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AGGRESSION, GUILT AND CATAPLEXY
American Journal of Psychiatry, 1953CATAPLEXY, a symptom of narcolepsy, is an illuminating example of paralysis of voluntary movement induced by emotion. In all the domain of psychosomatic medicine cataplexy is almost without a peer as a compelling illustration of how emotion can give rise, immediately and dramatically, to a physical symptom.
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A standardized test for cataplexy
Sleep Medicine, 2000This study developed a standardized procedure for provoking cataplexy, which facilitated observation of the physiologic changes occurring with cataplexy. Data were obtained from narcoleptic patients recruited from a sleep disorder center. Patients were asked to describe the nature and frequency of cataplexy, as well as their typical emotional triggers.
, Krahn +4 more
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Pseudocataplexy in narcolepsy with cataplexy
Sleep Medicine, 2010* Correspondence to: G. Plazzi, Sleep Disorders Center, Department of Neurological Sciences. University of Bologna, Via Ugo Foscolo, 7 40123 Bologna, Italy. Tel.: +39 051 2092926; fax: +39 051 2092963. ** Corresponding author at: Department of Neurology, UniversistatsSpital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland. Tel.: +41 044 2555503;
PLAZZI, GIUSEPPE +4 more
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Expert Opinion on Orphan Drugs, 2013
Introduction: The term cataplexy originates from the Greek κατά (kata, ‘down'), and πληξις (plexis, ‘stroke'). Cataplexy, a sudden loss of muscle tone in response to strong emotions is the most specific symptom of narcolepsy. It is thought to be due to disturbed rapid eye movement (REM) sleep regulation and portrayed as REM sleep atonia occurring at ...
Alberto K De la Herrán-Arita +2 more
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Introduction: The term cataplexy originates from the Greek κατά (kata, ‘down'), and πληξις (plexis, ‘stroke'). Cataplexy, a sudden loss of muscle tone in response to strong emotions is the most specific symptom of narcolepsy. It is thought to be due to disturbed rapid eye movement (REM) sleep regulation and portrayed as REM sleep atonia occurring at ...
Alberto K De la Herrán-Arita +2 more
openaire +1 more source