Results 11 to 20 of about 281,817 (339)

Current Trends in the Pharmacotherapy of Cataracts

open access: yesPharmaceuticals, 2020
Cataracts, one of the leading causes of preventable blindness worldwide, refers to lens degradation that is characterized by clouding, with consequent blurry vision.
Segewkal H. Heruye   +7 more
doaj   +2 more sources

Current Approach to the Pathogenesis of Diabetic Cataracts

open access: yesInternational Journal of Molecular Sciences, 2023
Cataracts remain the first or second leading cause of blindness in all world regions. In the diabetic population, cataracts not only have a 3–5 times higher incidence than in the healthy population but also affect people at a younger age.
M. Mrugacz   +3 more
semanticscholar   +1 more source

Inherited cataracts: molecular genetics, clinical features, disease mechanisms and novel therapeutic approaches

open access: yesBritish Journal of Ophthalmology, 2020
Cataract is the most common cause of blindness in the world; during infancy and early childhood, it frequently results in visual impairment. Congenital cataracts are phenotypically and genotypically heterogeneous and can occur in isolation or in ...
V. Berry   +5 more
semanticscholar   +1 more source

Methods and findings on an ophthalmic mission trip to colombia

open access: yesThe Pan-American Journal of Ophthalmology, 2020
Background: Medical ministry international (MMI) is a Canadian charitable organization that coordinates healthcare missions to underserved people in developing countries. Objective: We report on the baseline clinical findings of a mission trip to Ciénaga
Ethan Waisberg, John Harvey
doaj   +1 more source

Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization

open access: yesInternational Journal of Molecular Sciences, 2020
Gap junction-mediated intercellular communication facilitates the circulation of ions, small molecules, and metabolites in the avascular eye lens. Mutants of the lens fiber cell gap junction proteins, connexin46 (Cx46) and connexin50 (Cx50), cause ...
V. M. Berthoud   +5 more
semanticscholar   +1 more source

Study of congenital Morgagnian cataracts in Holstein calves [PDF]

open access: yes, 2019
Cataracts are focal to diffuse opacities of the eye lens causing impaired vision or complete blindness. For bilateral congenital cataracts in Red Holsteins a perfectly cosegregating mutation within the CPAMD8 gene (CPAMD8:g.5995966C>T) has been reported.
Beineke, Andreas   +9 more
core   +1 more source

Autoimmune polyglandular syndrome type 1 and eye damage

open access: yesActa Biomedica Scientifica, 2021
Autoimmune polyendocrine syndrome type 1 (APS type 1) is a disease characterized by a variety of clinical manifestations resulting from the involvement of multiple endocrine and non-endocrine organs in the pathological process.
L. Yu. Khamnueva   +3 more
doaj   +1 more source

Advances in pharmacotherapy of cataracts

open access: yesAnnals of Translational Medicine, 2020
Cataracts, the leading cause of vision impairment worldwide, arise from abnormal aggregation of lens proteins. According to the World Health Organization, cataracts cause more than 40% of blindness cases.
Jingjie Xu, Q. Fu, Xiangjun Chen, K. Yao
semanticscholar   +1 more source

Clinical Profile of Pediatric Cataracts in a Tertiary Eye Care Center in Mongolia

open access: yesCentral Asian Journal of Medical Sciences, 2022
Objective: To describe the clinical characteristics of pediatric cataracts in children undergoing surgery in our tertiary care center in Mongolia. Methods: Patients aged ≤ 18 years who underwent pediatric cataract surgery over a three-year period at our ...
Shamsiya Murat   +4 more
doaj   +1 more source

An epidemiological assessment of lens opacifications that impaired vision in patients injected with radium-224 [PDF]

open access: yes, 1988
The incidence of lens opacifications that impaired vision (cataract) was analyzed among 831 patients who were injected with known dosages of 224Ra in Germany shortly after World War II.
Chmelevsky, D.   +4 more
core   +1 more source

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