Results 211 to 220 of about 78,308 (305)

Microwave‐assisted one‐pot synthesis of MXene–rGO–Au nanocomposites for high‐sensitivity dopamine detection

open access: yesVIEW, EarlyView.
MXene/rGO/Au nanocomposites on a modified glassy carbon electrode enable rapid, sensitive DA detection with strong selectivity and reliable real‐sample recovery. The one‐pot microwave synthesis delivers a conductive, high‐performance platform for practical electrochemical DA sensing.
Farah Ezzah Ab Latif   +6 more
wiley   +1 more source

Biomimetic PB@PDA‐CA@Mem nanoplatform regulates oxidative stress and inflammatory microenvironment to enhance stroke recovery

open access: yesVIEW, EarlyView.
PB@PDA‐CA@Mem enhances ischemic brain accumulation and enables acid‐responsive CA release. Through broad‐spectrum ROS/RNS scavenging, Nrf2/Keap1 activation, and NF‐κB/NLRP3 suppression, it alleviates oxidative stress and neuroinflammation, preserves neuronal architecture, reduces infarction, and improves functional recovery.
Lei Shi   +9 more
wiley   +1 more source

Yeast Knockout Strain Collection: Driving Functional Genomics, Biotechnological Applications and Human Disease Research

open access: yesYeast, EarlyView.
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley   +1 more source

Impact of a High‐Fiber, Fruitless Diet on the Gut Microbiome, and Health of Captive Orangutans

open access: yesZoo Biology, EarlyView.
Transitioning captive orangutans to a high‐fiber, fruitless diet improved gut microbiome diversity, enhanced gastrointestinal health, and reduced stress‐related behaviors. This study demonstrates the significant benefits of tailored dietary interventions in promoting the health and welfare of zoo‐housed primates.
Camille Duvivier   +10 more
wiley   +1 more source

Repurposed catechol‐O‐methyltransferase inhibitors tolcapone and entacapone preferentially suppress aggregation and seeding of P301 mutant tau in human neuronal models

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Pathogenic aggregation and propagation of seed‐competent TAU assemblies drive tauopathies. MAPT P301 mutations accelerate aggregation and enhance seed competence, yet pharmacological strategies selectively targeting these pathogenic species remain limited.
Ihor Kozlov   +6 more
wiley   +1 more source

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