Results 221 to 230 of about 64,002 (290)

Top-down enrichment of oil-degrading microbial consortia reveals functional streamlining and novel degraders. [PDF]

Front Microbiol
Wu H, Du X, Zheng J, Li X, Song Q, Yan Y, Ma A, Xu A, Li J.   +8 more
europepmc   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Vasopressor Strategy in Pediatric Sepsis: A Clinical Pharmacology Perspective. [PDF]

J Pediatr Pharmacol Ther
Green DJ, Watt KM.
europepmc   +1 more source

Catechol Amines in Bananas

Journal of Pharmacy and Pharmacology, 1958
openaire   +2 more sources

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, EarlyView.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

A multi-omics analysis unveils functional and regulatory links between hydroxybenzene and aromatic amino acid metabolism in <i>Candida albicans</i>. [PDF]

mSystems
Garbe E, Schäuble S, Böttcher B, Jesse R, Driesch D, van Wilijck L, Elshafee O, Schille TB, Hube B, Panagiotou G, Vylkova S.   +10 more
europepmc   +1 more source

[Catechol estrogens].

Ginekologia polska, 1986
openaire   +1 more source

Sterically hindered catechol-derived Schiff bases: design, synthesis, SAR analysis and mechanisms of the antioxidant activity. [PDF]

RSC Med Chem
Gvozdev M, Turomsha I, Osipovich N, Sverdlov R, Loginova N.   +4 more
europepmc   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Metal surface-triggered DNAzyme catalysis for efficient DNA cleavage. [PDF]

Commun Chem
Jiang F, Dong Y, Yu W, Tian H, Yang L, Jia Z, Sheng Y, Si D, Xu J, Jiang D.   +9 more
europepmc   +1 more source