Results 31 to 40 of about 33,328 (231)
Bananas decrease acetaminophen potency in in vitro assays. [PDF]
PLoS ONE, 2018 Edible portions of bananas contain high levels of polyphenol oxidase, which catalyzes reactions in the melanin formation pathway. Tyrosine, a physiological substrate of polyphenol oxidase, has an analogous structure to acetaminophen.
Yoshihiro Uesawa, Naotaka Tsuji
doaj +1 more source
Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]
, 2016 Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June +3 more
core +2 more sources
MONOAMINE OXIDASE AND CATECHOL- O-METHYLTRANSFERASE INHIBITORS
Medical Clinics of North America, 1999 Despite advances in the treatment of PD, there remain significant unmet therapeutic needs. This is particularly true at the later stages of the disease when dopaminergic therapy is complicated by motor fluctuations and dyskinesias. Inhibition of dopamine metabolism is a valuable adjunct to exogenous dopaminergic replacement.
A, Siderowf, R, Kurlan
openaire +2 more sources
Chemosensors, 2014 Inhibition-based biosensors were developed by immobilizing tyrosinase (Tyr, polyphenol oxidase) from the crude extract of avocado fruit on electrochemically prepared polypyrrole (PPy) films.
André Brisolari, Débora Gonçalves
doaj +1 more source
Rate enhancement of the catechol oxidase activity of a series of biomimetic monocopper(II) complexes by introduction of non-coordinating groups in N-tripodal ligands [PDF]
, 2012 International audienceAsymmetrical N-tripodal ligands have been synthesized in three steps. Diversity has been introduced at the first step of the synthesis by adding pyrazine, pyridine, benzyl and thiophene rings.
Floner, Didier +5 more
core +4 more sources
Química Nova, 2016 This work applies the Density Functional Theory (DFT) to study binuclear complexes of Mn2+ with the ligand 2-hydroxibenzilglycine and its substituted derivatives. The results showed the isomer 2 with multiplicity 11-ete as the most stable between all the
Everton T. da Silva +2 more
doaj +1 more source
eNeurologicalSci, 2020 Background: Dopamine replacement therapy is an established treatment for motor symptoms of Parkinson's disease, but its long-term use is often limited by the eventual development of motor complications, including levodopa-induced dyskinesia.
Shoko Kakinuma +19 more
doaj +1 more source
Induction of Systemic Resistance in Tomato against Ralstonia Solanacearum By Pseudomonas Fluorescens [PDF]
, 2014 The biological control agent Pseudomonasfluorescens was used against the bacterial wilt causing Ralstoniasolanacearum. The present investigation focuses on the role of defenserelated enzymes in imparting resistance in tomato against R. solanacearum.
Chitrashree, C. Srinivas. +2 more
core +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Chemistry of Inorganic MaterialsThe motivation to find functional models of different metalloenzymes comes from their potential to develop better catalysts inspired by nature. Generally, metalloenzymes can activate aerial dioxygen due to the metal ions in it.
Kousik Ghosh +5 more
doaj +1 more source