Results 31 to 40 of about 20,124 (183)

Estudo teórico de complexos binucleares de manganês(II) com o ligante 2-hidroxibenzilglicina, possíveis miméticos para a catecol oxidase

Química Nova, 2016
This work applies the Density Functional Theory (DFT) to study binuclear complexes of Mn2+ with the ligand 2-hydroxibenzilglycine and its substituted derivatives. The results showed the isomer 2 with multiplicity 11-ete as the most stable between all the
Everton T. da Silva, Annelise Casellato, Sérgio de P. Machado   +2 more
doaj   +1 more source

Monoamine oxidase B rs1799836 G allele polymorphism is a risk factor for early development of levodopa-induced dyskinesia in Parkinson's disease

eNeurologicalSci, 2020
Background: Dopamine replacement therapy is an established treatment for motor symptoms of Parkinson's disease, but its long-term use is often limited by the eventual development of motor complications, including levodopa-induced dyskinesia.
Shoko Kakinuma, Minako Beppu, Setsu Sawai, Akitoshi Nakayama, Shigeki Hirano, Yoshitaka Yamanaka, Tatsuya Yamamoto, Chigusa Masafumi, Xiamuxiya Aisihaer, Alimasi Aersilan, Yue Gao, Kenichi Sato, Itoga Sakae, Takayuki Ishige, Motoi Nishimura, Kazuyuki Matsushita, Mamoru Satoh, Fumio Nomura, Satoshi Kuwabara, Tomoaki Tanaka   +19 more
doaj   +1 more source

Developmental changes in human dopamine neurotransmission: cortical receptors and terminators

BMC Neuroscience, 2012
Background Dopamine is integral to cognition, learning and memory, and dysfunctions of the frontal cortical dopamine system have been implicated in several developmental neuropsychiatric disorders.
Rothmond Debora A, Weickert Cynthia S, Webster Maree J   +2 more
doaj   +1 more source

Mineral composition of Aegle marmelos (L.) corrêa ash: Exploration of its ability to mimic the function of different metalloenzymes

Chemistry of Inorganic Materials
The motivation to find functional models of different metalloenzymes comes from their potential to develop better catalysts inspired by nature. Generally, metalloenzymes can activate aerial dioxygen due to the metal ions in it.
Kousik Ghosh, K. Vamsee Krishna, T. Vinodkumar, T. Dinesh, R. Balakumar, S. Chitra   +5 more
doaj   +1 more source

MONOAMINE OXIDASE AND CATECHOL- O-METHYLTRANSFERASE INHIBITORS

Medical Clinics of North America, 1999
Despite advances in the treatment of PD, there remain significant unmet therapeutic needs. This is particularly true at the later stages of the disease when dopaminergic therapy is complicated by motor fluctuations and dyskinesias. Inhibition of dopamine metabolism is a valuable adjunct to exogenous dopaminergic replacement.
A, Siderowf, R, Kurlan
openaire   +2 more sources

Concentration of norepinephrine, serotonin, and histamine, and of amine-metabolizing enzymes in mammalian adipose tissue

Journal of Lipid Research, 1963
The norepinephrine content of adipose tissue is shown to be very different in various animal species and different sites of origin, ranging from 0.03-1.4 μg/g. Adipose tissue also contains considerable amounts of serotonin (0.01-1.04 μg/g) and histamine (
K. Stock, E.O. Westermann
doaj   +1 more source

Potential Use of Apple Polyphenol Oxidase for Bioremediation of Phenolic Contaminants [PDF]

Kemija u Industriji, 2018
Phenolic compounds, such as catechol, are released into the environment from a variety of industrial sources and they present a serious ecosystem burden.
Anita Šalić, Ivica Strelec, Bruno Zelić, Marina Tišma   +3 more
doaj   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Boosting LPMO-driven lignocellulose degradation by polyphenol oxidase-activated lignin building blocks

Biotechnology for Biofuels, 2017
Background Many fungi boost the deconstruction of lignocellulosic plant biomass via oxidation using lytic polysaccharide monooxygenases (LPMOs). The application of LPMOs is expected to contribute to ecologically friendly conversion of biomass into fuels ...
Matthias Frommhagen, Sumanth Kumar Mutte, Adrie H. Westphal, Martijn J. Koetsier, Sandra W. A. Hinz, Jaap Visser, Jean-Paul Vincken, Dolf Weijers, Willem J. H. van Berkel, Harry Gruppen, Mirjam A. Kabel   +10 more
doaj   +1 more source

Citrate-Coated Platinum Nanoparticles Exhibit a Primary Particle-Size Dependent Effect on Stimulating Melanogenesis in Human Melanocytes

Cosmetics, 2020
Hypopigmentation disorders due to an underproduction of the pigment melanin by melanocytes cause uneven skin coloration, while in hair follicles they cause grey hair.
Shilpi Goenka, Jimmy Toussaint
doaj   +1 more source