Results 71 to 80 of about 306,357 (240)

Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall, Henry G. Box, Karl A. P. Payne, Stephen A. Marshall, David Leys   +4 more
wiley   +1 more source

Purification and Biochemical Characterization of Polyphenol Oxidase Extracted from Wheat Bran (Wan grano)

Molecules
Currently, little is known about the characteristics of polyphenol oxidase from wheat bran, which is closely linked to the browning of wheat product. The wheat PPO was purified by ammonium sulfate precipitation, DEAE-Sepharose ion-exchange column, and ...
Kun Yu, Wei He, Xiaoli Ma, Qi Zhang, Chunxu Chen, Peiyan Li, Di Wu   +6 more
doaj   +1 more source

New copper(II) μ-alkoxo-μ-carboxylato double-bridged complexes as models for the active site of catechol oxidase: synthesis, spectral characterization and DFT calculations. [PDF]

Heliyon, 2022
Patel AK, Patel N, Patel RN, Jadeja RN.
europepmc   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Spectroscopic, Electrochemical, Catechol oxidase and catalaselike Activities of New Copper(II) Tweezers of Benzimidazole Incorporating Amino Acid Moieties

International Journal of Electrochemical Science, 2014
Two mixed ligand complexes, viz., [Cu(BzOH)(Gly)]ClO4 1 and [Cu(BzOH)(Glu)]ClO4 2, where BzOH = 1-benzimidazolylethanol, Gly = Glycine, and Glu = L-glutamic acid were synthesized Their structures and properties were characterized by elemental analysis ...
Mohamed M. Ibrahim, Gaber A.M. Mersal, Abdel-Motaleb M. Ramadan, Samir A. El-Shazly, Mahmoud A. Amin   +4 more
doaj   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

A Cu-bis(imidazole) Substrate Intermediate Is the Catalytically Competent Center for Catechol Oxidase Activity of Copper Amyloid-β. [PDF]

Inorg Chem, 2021
Bacchella C, Dell'Acqua S, Nicolis S, Monzani E, Casella L.   +4 more
europepmc   +1 more source

Methylglyoxal Affects Dopamine Homeostasis in SH‐SY5Y Cells Through the Modulation of miR‐190a and miR‐214

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Alessandra Croce, Paola Mirra, Francesca Chiara Pignalosa, Federica Zatterale, Immacolata Prevenzano, Domenico Conza, Luca Ulianich, Claudia Miele, Francesco Beguinot, Francesca Fiory   +9 more
wiley   +1 more source

Development of a Polyphenol Oxidase Biosensor from Jenipapo Fruit Extract (Genipa americana L.) and Determination of Phenolic Compounds in Textile Industrial Effluents

Biosensors, 2018
In this work, an innovative polyphenol oxidase biosensor was developed from Jenipapo (Genipa americana L.) fruit and used to assess phenolic compounds in industrial effluent samples obtained from a textile industry located in Jaraguá-GO, Brasil.
Rafael Souza Antunes, Denes Ferraz, Luane Ferreira Garcia, Douglas Vieira Thomaz, Rafael Luque, Germán Sanz Lobón, Eric de Souza Gil, Flávio Marques Lopes   +7 more
doaj   +1 more source

Detection of Catechol Using a Biosensor Based on Biosynthesized Silver Nanoparticles and Polyphenol Oxidase Enzymes

Portugaliae Electrochimica Acta, 2019
In the present work, we report the development of a polyphenol oxidase (PPO) sensor for the selective and sensitive detection of catechol, using biosynthesized silver nanoparticles (AgNPs).
S. Sandeep, A. S. Santhosh, N. K. Swamy, G. Suresh, J. Melo   +4 more
semanticscholar   +1 more source