Results 161 to 170 of about 329,157 (308)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Formalization of ∞-Category Theory [PDF]

open access: yes
The field of category theory has served as an excellent tool to unify and translate between constructions and theorems across different subfields in mathematics, but also computer science and physics.
Weinberger, Jonathan
core  

Category Theory

open access: yes
This book provides a deep foray into category theory, presenting a unique approach to exploring diverse branches of mathematics. From the fundamentals, where the definitions of morphism, object and composition in categories are established, to the application of these concepts in real analysis, linear algebra and general topology, my purpose is to ...
  +5 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

METHOD FOR PROCESSING SUBJECTIVE EXPERT INFORMATION FOR DECISION MAKING USING FUZZY SETS THEORY

open access: yesМодели, системы, сети в экономике, технике, природе и обществе
Background. Decision making issues are key for any organization. The problem in the decision-making process is the high uncertainty regarding the results of decisions made due to the subjectivity of experts.
V.V. Antonov, K.A. Konev
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

An Introduction to Category Theory [PDF]

open access: yes
Category theory is a relatively new field of mathematics that has grown much in popularity in recent years. It is a general theory of mathematical structure that lends itself to making overarching, yet deep, connections between many branches of ...
Kopp, Joseph
core   +1 more source

Commentary: Experimental evidence for compositional syntax in bird calls

open access: yesFrontiers in Psychology, 2016
Steven Phillips, William Hulme Wilson
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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