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Cadherins and catenins in development

Current Opinion in Cell Biology, 1996
Cadherins and catenins represent key molecules during development. Recent findings demonstrate the involvement of cadherins and catenins in signaling pathways. In a working hypothesis, signaling via beta-catenin regulates the epithelial-mesenchymal transition in vertebrate development.
Christiane Bierkamp   +2 more
openaire   +3 more sources

α-catenin, β-catenin and P-120-catenin immunoexpression in canine mammary tissues and their relationship with E-cadherin

Research in Veterinary Science, 2020
Mammary tumors represent the second most common neoplasia in the canine species, where more than 50% of the cases are classified as malignant. The histological classification is used as a prognostic tool. Cadherins and catenins are responsible for cell adhesion and are intrinsic connected with the process of metastasis.
Júlio Carvalheira   +3 more
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In Vivo Functions of Catenins [PDF]

open access: possible, 2004
The adhesion of cells to neighbor cells determines cellular and tissue morphogenesis and regulates major cellular processes including motility, growth, survival, and differentiation. Regions of cell-cell adhesion are adherens junctions, desmosomes, and tight junctions.
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The reduced expression of e-cadherin, alpha-catenin and gamma-catenin but not beta-catenin in human lung cancer.

Oncology Reports, 1999
Cadherins are Ca2+-dependent cell-cell adhesion molecules, and are involved in the formation and maintenance of the histo-architecture. Using a combination of biochemical and immunohistochemical methods, we analyzed the expression of cadherin-catenin complexes in 37 non-small cell lung carcinomas. In 19 cases, decreased expression of E-cadherin protein
Hidehiko Matsumoto   +8 more
openaire   +3 more sources

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