Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]
Cell Host & Microbe, 2015 Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta +1 more
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Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial. [PDF]
, 2017 More efficacious treatment regimens are needed for tuberculosis, however, drug development is impeded by a lack of reliable biomarkers of disease severity and of treatment effect. We conducted a directed screen of host biomarkers in participants enrolled
Barbero, S +14 more
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مجله كليه طب الكندي, 2023 Background: Vitamin D improves innate immunity by enhancing the expression of antimicrobial peptides. The antimicrobial action of cathelicidin is widespread and effective against cariogenic bacteria.
Narjes M. Alhelfi, Nibal M. Hobi
doaj +1 more source
Immune gene expression profiling of Proliferative Kidney Disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and T helper cell-like activities [PDF]
, 2013 Peer reviewedPublisher ...
Gorgoglione, Bartolomeo +3 more
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Plasma cathelicidin and longitudinal lung function in current and former smokers.
PLoS ONE, 2019 IntroductionCathelicidin (also known as LL-37 in humans) is an antimicrobial peptide secreted by epithelial and immune cells and regulated by vitamin D. The immunological roles of cathelicidin make it a putative biomarker to identify individuals at risk ...
Robert M Burkes +6 more
doaj +1 more source
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics [PDF]
, 2016 Mastitis, inflammation of the mammary gland, is the most common and costly disease of dairy cattle in the western world. It is primarily caused by bacteria, with Streptococcus uberis as one of the most prevalent causative agents.
Burchmore, Richard +10 more
core +1 more source
A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]
, 2020 A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven +7 more
core +1 more source
PLoS ONE, 2011 BackgroundEpithelial surfaces such as the gastrointestinal mucosa depend on expression of antimicrobial peptides like cathelicidin for immune defence against pathogens.
Dorothee Rogoll +4 more
doaj +1 more source
The roles of vitamin D and cathelicidin in type 1 diabetes susceptibility
Endocrine Connections, 2021 Type 1 diabetes has an increasingly greater incidence and prevalence with no cure available. Vitamin D supplementation is well documented to reduce the risk of developing type 1 diabetes.
Cecília Cristelo +3 more
doaj +1 more source
Cathelicidin deficiency predisposes to eczema herpeticum [PDF]
Journal of Allergy and Clinical Immunology, 2006 The cathelicidin family of antimicrobial peptides is an integral component of the innate immune response that exhibits activity against bacterial, fungal, and viral pathogens. Eczema herpeticum (ADEH) develops in a subset of patients with atopic dermatitis (AD) because of disseminated infection with herpes simplex virus (HSV).This study investigated ...
Michael D, Howell +8 more
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