Results 81 to 90 of about 24,668 (220)

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Cathelicidin-OA1, a novel antioxidant peptide identified from an amphibian, accelerates skin wound healing

Scientific Reports, 2018
Cathelicidins play pivotal roles in host defense. The discovery of novel cathelicidins is important research; however, despite the identification of many cathelicidins in vertebrates, few have been reported in amphibians.
Xiaoqing Cao, Ying Wang, Chunyun Wu, Xiaojie Li, Zhe Fu, Meifeng Yang, Wenxin Bian, Siyuan Wang, Yongli Song, Jing Tang, Xinwang Yang   +10 more
doaj   +1 more source

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

EMBO Molecular Medicine, 2021
Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a ...
Zhili Deng, Mengting Chen, Yingzi Liu, San Xu, Yuyan Ouyang, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Jinmao Li, Qian Shi, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Hongbing Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Ji Li   +20 more
doaj   +1 more source

Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment-In vivo studies.

PLoS ONE, 2021
Cathelicidin (CRAMP) is a defence peptide with a wide range of biological responses including antimicrobial, immunomodulatory and wound healing. Due to its original properties the usefulness of CRAMP in the treatment of pulmonary fibrosis was assessed in
Marta Kinga Lemieszek, Katarzyna Sawa-Wejksza, Marcin Golec, Jacek Dutkiewicz, Jacek Zwoliński, Janusz Milanowski   +5 more
doaj   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

Molecular Therapy: Oncolytics, 2019
The antimicrobial peptide cathelicidin inhibits development of colitis-associated colon cancer. However, the role of cathelicidin in colon cancer metastasis remains unknown.
Jiani Wang, Michelle Cheng, Ivy K.M. Law, Christina Ortiz, Mingjun Sun, Hon Wai Koon   +5 more
doaj   +1 more source

Cathelicidin and Calprotectin Are Disparately Altered in Murine Models of Inflammatory Arthritis and Airway Inflammation

Frontiers in Immunology, 2020
Cationic host defense peptides (CHDP) are immunomodulatory molecules that control infections and contribute to immune homeostasis. CHDP such as cathelicidin and calprotectin expression is altered in the arthritic synovium, and in the lungs of asthma and ...
Mahadevappa Hemshekhar, Hadeesha Piyadasa, Hadeesha Piyadasa, Dina Mostafa, Dina Mostafa, Leola N. Y. Chow, Andrew J. Halayko, Andrew J. Halayko, Neeloffer Mookherjee, Neeloffer Mookherjee, Neeloffer Mookherjee   +10 more
doaj   +1 more source

Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense [PDF]

, 2017
Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host.
Tang, Xiao
core   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Journal of Inflammation Research, 2021
Paulina Krawiec, Elżbieta Pac-Kożuchowska Department of Pediatrics and Gastroenterology, Medical University of Lublin, Lublin, PolandCorrespondence: Paulina KrawiecDepartment of Pediatrics and Gastroenterology, Medical University of Lublin, Racławickie 1,
Krawiec P, Pac-Kożuchowska E
doaj