Results 291 to 300 of about 13,268,265 (360)

Fisetin-loaded nanoemulsion ameliorates lung cancer pathogenesis via downregulating cathepsin-B, galectin-3 and enolase in an in vitro setting. [PDF]

EXCLI J
Saeid AB, Paudel KR, De Rubis G, Mehndiratta S, Kokkinis S, Vishwas S, Yeung S, Gupta G, Singh SK, Dua K.   +9 more
europepmc   +1 more source

Isolation of Novel Peptides, Cabin-1, -2, -3, and -4, That Inhibit Cathepsin B from a Thermolysin Digest of Human Plasma.

, 2002
Kazuya Nakagomi, Akiyoshi Fujimura, Hiromi Maeda, Yutaka Sadakane, Noriko Fujii, Toshifumi Akizawa, Takenori Tanimura, Yasumaru Hatanaka   +7 more
openalex   +2 more sources

Sexual Selection on Non‐Ornamental Traits Is Underpinned by Evidence of Genetic Constraints on Sex‐Biased Expression in Dusky Pipefish

Molecular Ecology, EarlyView.
ABSTRACT Species lacking distinct secondary sex characteristics, such as differences in size or morphology, are often thought to experience lower levels of sex‐specific selection in comparison to highly sexually dimorphic organisms. However, monomorphism in classic visible traits could be a result of genetic or physiological constraints that prevent ...
Nicole M. Tosto, Emily Rose, Heather D. Mason, Judith E. Mank, Sarah P. Flanagan   +4 more
wiley   +1 more source

The Effects of Cathepsin B Inhibition in the Face of Diffuse Traumatic Brain Injury and Secondary Intracranial Pressure Elevation. [PDF]

Biomedicines
Hernandez M, Regan S, Ansari R, Logan-Wesley A, Lilova R, Levi C, Gorse K, Lafrenaye A.   +7 more
europepmc   +1 more source

Resources Modulate Developmental Shifts but Not Infection Tolerance Upon Co‐Infection in an Insect System

Molecular Ecology, EarlyView.
ABSTRACT Energetic resources within organisms fuel both parasite growth and immune responses against them, but it is unclear whether energy allocation is sufficient to explain changes in infection outcomes under the threat of multiple parasites. We manipulated diet in flour beetles (Tribolium confusum) infected with two natural parasites and used a ...
Nora K. E. Schulz, Danial Asgari, Siqin Liu, Stephanie S. L. Birnbaum, Alissa M. Williams, Arun Prakash, Ann T. Tate   +6 more
wiley   +1 more source

Cysteine protease cathepsin B promotes lysosome integrity to extend the lifespan of alternative day fasting worms. [PDF]

Aging Cell
Yin X, Dai F, Ran D, Zhang Y, Qu Z, Zheng S.   +5 more
europepmc   +1 more source

Mass spectrometry reveals age‐dependent collagen decline in murine atria

Annals of the New York Academy of Sciences, EarlyView.
Using mass spectrometry, we analyzed the atrial ECM of young (12 weeks) and old (77 weeks) C57BL/6J mice. Results showed a marked decrease in collagen content with age, alongside increases in specific ECM‐related proteins (e.g., MMP9, S100A9, VWA3A).
Nathalie Ringström, Charlotte Edling, Giovanna Nalesso, Javier Barallobre‐Barreiro, Kamalan Jeevaratnam   +4 more
wiley   +1 more source

Extracellular vesicle proteome unveils cathepsin B connection to Alzheimer's disease pathogenesis. [PDF]

Brain
Yuyama K, Sun H, Fujii R, Hemmi I, Ueda K, Igeta Y.   +5 more
europepmc   +1 more source

Towards Aptamer-Targeted Drug Delivery to Brain Tumors: The Synthesis of Ramified Conjugates of an EGFR-Specific Aptamer with MMAE on a Cathepsin B-Cleavable Linker. [PDF]

Pharmaceutics
Brylev VA, Ryabukhina EV, Nazarova EV, Samoylenkova NS, Gulyak EL, Sapozhnikova KA, Dzarieva FM, Ustinov AV, Pronin IN, Usachev DY, Kopylov AM, Golovin AV, Pavlova GV, Ryazantsev DY, Korshun VA.   +14 more
europepmc   +1 more source