Results 241 to 250 of about 118,840 (299)

Action of cathepsin C on dipeptide esters.

The Yale journal of biology and medicine, 2003
D S, WIGGANS, M, WINITZ, J S, FRUTON
openaire   +1 more source

RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi, Giulia Gentili, Laura Salvadori, Martina Paiella, Marcello Manfredi, Vittoria Federica Borrini, Kaamashri Mangar, Ann Marie Schmidt, Maurizio Muscaritoli, Francesca Riuzzi, Guglielmo Sorci   +10 more
wiley   +1 more source

GPN does not release lysosomal Ca²⁺ but evokes Ca²⁺ release from the ER by increasing the cytosolic pH independently of cathepsin C.

J Cell Sci, 2019
Atakpa P, van Marrewijk LM, Apta-Smith M, Chakraborty S, Taylor CW.   +4 more
europepmc   +1 more source

Bone adhesive with temporally-synchronized degradation for enhanced osteointegration. [PDF]

Bone Res
Gu JT, Li ZT, Wang YZ, Hao DX, Dang GP, Cao XQ, Tay FR, Chen JH, Aparicio C, Jiao K, Niu LN.   +10 more
europepmc   +1 more source

Fibronectin type III domain-containing protein 5/irisin in extracellular vesicles is reduced in older individuals. [PDF]

Brain Commun
Hunter TR, Lyra E Silva NM, de Freitas GB, Rody T, Santos LE, Zhang J, Bullock A, Tartaglia MC, Abraham S, Nicolini C, Nelson AJ, Heisz JJ, Fahnestock M, De Felice FG.   +13 more
europepmc   +1 more source

Cathepsin Inhibitor Suppresses the Growth of Ectopic Hepatocellular Carcinoma Tumors in Mouse Models. [PDF]

ACS Pharmacol Transl Sci
Crown O, Odubanjo OV, Adeyinka OS, Noubissi FK, Ogungbe IV.   +4 more
europepmc   +1 more source

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Cathepsin C: An allosteric enzyme

Biochimica et Biophysica Acta (BBA) - Enzymology, 1970
Abstract 1. 1. Cathepsin C requires Cl− for activity. Activation is also found with bromide, iodide, thiocyanate, nitrate, and chlorate. 2. 2. At saturating activator concentrations, substrates are split according to Michaelis-Menten kinetics; at non-saturating concentrations cooperativity is observed.
J, Gorter, M, Gruber
openaire   +2 more sources

CATHEPSIN B, CATHEPSIN C AND ARYLAMIDASE IN RABBIT CORNEA

Acta Ophthalmologica, 1982
The 3 peptide hydrolases cathepsin B, cathepsin C and arylamidase have been assayed in rabbit cornea with the use of fluorigenic derivatives of β‐naphthylamine. The optimal reaction conditions and kinetic properties are described. The assay procedures which are simple and very sensitive can be used for studying the release of these enzymes from corneal
K, Schive, G, Volden
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The catalytic properties of cathepsin C

Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964
Abstract 1. 1. The catalytic properties of the intracellular peptidase cathepsin C (EC 3.4.4.9) were investigated. The enzyme is devoid of the proteolytic activity that had been ascribed to it. 2. 2. Cathepsin C has a very narrow specificity.
R J, PLANTA, J, GORTER, M, GRUBER
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Intracellular distribution of cathepsin B and cathepsin C in rat liver

Biochimica et Biophysica Acta (BBA) - Enzymology and Biological Oxidation, 1966
Summary 1. The intracellular distribution of cathepsin B and cathepsin C (EC 3,4,4.9) in rat liver has been investigated by means of differential and density-equilibrium centrifugation, activation and solubilization experiments. 2. The enzymes appear to be localized in the lysosomes.
J M, Bouma, M, Gruber
openaire   +2 more sources