Results 141 to 150 of about 94,685 (278)

Functions of cathepsin K in bone resorption - Lessons from cathepsin K deficient mice

, 2018
Cathepsin K is a cysteine proteinase expressed predominantly in osteoclasts. Cathepsin K cleaves key bone matrix proteins and is believed to play an important role in degrading the organic phase of bone during bone resorption. Pycnodysostosis, an autosomal recessive osteosclerosing skeletal disorder has recently been shown to result from mutations in ...
Saftig, P., Hunziker, Ernst B., Everts, V., Jones, Simon, Boyde, A., Wehmeyer, O., Suter, A., von Figura, Kurt, Langner, Jürgen, Ansorge, Siegfried   +9 more
openaire   +1 more source

Effect of calcium chloride injection and freezing prior to wet aging on the meat quality of cull cows

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND In Brazil, the slaughter of female cattle, particularly older animals, has increased substantially. However, meat from this category presents limitations in terms of quality, mainly because of its toughness resulting from a high concentration of cross‐links between collagen fibers.
Juliano CC Belmonte, Taynara S Santana, Micheline F Castro, Rosileide V Rohod, Marcelo Vedovatto, Aylpy RD Santos, Henrique J Fernandes, Dalton M Oliveira   +7 more
wiley   +1 more source

Proteinases [PDF]

, 1993
Fritz, Hans, Jochum, Marianne, Machleidt, W., Neuhof, H., Redl, H., Schlag, Günther   +5 more
core   +1 more source

Antimicrobial Cyclic Peptidomimetics

Macromolecular Rapid Communications, EarlyView.
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley   +1 more source

Cathepsin K-Activated Probe for Fluoro-Photoacoustic Imaging of Early Osteolytic Metastasis. [PDF]

Adv Sci (Weinh), 2023
Song Z, Miao J, Miao M, Cheng B, Li S, Liu Y, Miao Q, Li Q, Gao M.   +8 more
europepmc   +1 more source

Tumor Cell Migration May Be an Inherent “Foraging” Behavior

Medicine Advances, EarlyView.
Tumor cells gradually form pseudopodia, migrate to necrotic cells, make contact with them, and absorb necrotic cell debris. During this migration, small vesicles formed by dying tumor cells also gradually migrate toward living tumor cells. Once the nutrients from the necrotic cells have been completely absorbed, the living tumor cells will leave ...
Fuqian Zhao, Hongmei Niu, Lusi Zhang, Daofu Shen, Lei Wang   +4 more
wiley   +1 more source

Enhanced BMP signaling in Cathepsin K-positive tendon progenitors induces heterotopic ossification. [PDF]

Biochem Biophys Res Commun, 2023
Yamaguchi H, Li M, Kitami M, Swaminathan S, Mishina Y, Komatsu Y.   +5 more
europepmc   +1 more source

Proteolytic enzyme systems [PDF]

, 1993
Fritz, Hans, Jochum, Marianne, Machleidt, W., Redl, H., Schlag, Günther   +4 more
core   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

The role of lysosomal cysteine proteinases as markers of macrophage activation and as non-specific mediators of inflammation [PDF]

, 1993
Assfalg-Machleidt, Irmgard, Billing, A., Faist, E., Fröhlich, D., Jochum, Marianne, Joka, T., Machleidt, W., Meakins, J., Nast-Kolb, Dieter, Schildberg, F. W.   +9 more
core   +1 more source