Results 171 to 180 of about 94,685 (278)

Targeting Cathepsin K to Accelerate Diabetic Wound Healing. [PDF]

ACS Pharmacol Transl Sci
Chenchar A, Mattos Pereira V, Apte A, Lyttle BD, Vaughn AE, Lehmann T, Bardill JR, Zgheib C, Liechty KW, Roballo KCS, Zhang Z, Alexander BM, Nair S.   +12 more
europepmc   +1 more source

Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen. [PDF]

Life Sci Alliance, 2023
Fabrik I, Bilkei-Gorzo O, Öberg M, Fabrikova D, Fuchs J, Sihlbom C, Göransson M, Härtlova A.   +7 more
europepmc   +1 more source

Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]

, 2018
Bukowska-Straková, Karolina, Dulak, Józef, Florczyk-Soluch, Urszula, Józefczuk, Ewelina, Józkowicz, Alicja, Mendel, Mateusz, Nowak, Witold, Stępniewski, Jacek, Viscardi, Monika   +8 more
core   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Circulatory cathepsin K as biomarkers in older adults with sarcopenia: a case-control study. [PDF]

Front Med (Lausanne)
Liu H, Liu H, Xing Y, Wang G, Wang J, Fan Y, Zhang P, Wang S, Zhang H.   +8 more
europepmc   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Cathepsin K: a novel association with glucose intolerance, insulin resistance, and subclinical atherosclerosis in T2DM. [PDF]

J Transl Med
Averta C, Rubino M, Mancuso E, Massimino M, Coppolino G, Bolignano D, Cassano V, Greco M, Palummo A, Sciacqua A, Perticone M, Mannino GC, Sesti G, Andreozzi F.   +13 more
europepmc   +1 more source

Visualizing Cathepsin K-Cre Expression at the Single-Cell Level with GFP Reporters. [PDF]

JBMR Plus, 2023
Chai W, Hao W, Liu J, Han Z, Chang S, Cheng L, Sun M, Yan G, Liu Z, Liu Y, Zhang G, Xing L, Chen H, Liu P.   +13 more
europepmc   +1 more source

Pathobiochemistry of Sepsis [PDF]

, 1986
Duswald, Karl-Heimo, Fritz, Hans, Inthorn, D., Jochum, Marianne, Welter, H. F., Witte, J.   +5 more
core   +1 more source

Diagnosing oncocytic renal tumours on renal mass biopsy; pathological concordance and the impact of evolving classification

Histopathology, EarlyView.
Overall, there was good concordance between renal mass biopsy and subsequent diagnosis at nephrectomy or repeat biopsy in oncocytic renal neoplasms. Some discordant cases were reclassified as emerging tumour entities (LOT, EVT), indicating that greater recognition of these entities may help reduce diagnostic uncertainty and improve biopsy ...
Shifaa' Al Qa'qa', Carol C Cheung, Satheesh Krishna, Antonio Finelli, Susan Prendeville   +4 more
wiley   +1 more source