Results 191 to 200 of about 94,685 (278)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis. [PDF]

JBMR Plus
Panwar P, Olesen JB, Delaisse JM, Søe K, Brömme D.   +4 more
europepmc   +1 more source

Cathepsin K: A Versatile Potential Biomarker and Therapeutic Target for Various Cancers. [PDF]

Curr Oncol, 2022
Qian D, He L, Zhang Q, Li W, Tang D, Wu C, Yang F, Li K, Zhang H.   +8 more
europepmc   +1 more source

Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding

Oral Diseases, EarlyView.
ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior, Clovis Bergamin Griso, Amanda Borges Pirondi, Laura Teodoro de Marchi, Talita Mendes Oliveira Ventura, Larissa Tercilia Grizzo, Roosevelt da Silva Bastos, Alejandra Chaparro, Nagihan Bostanci, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source

mTOR eosinophilic renal cell carcinoma: a distinctive tumor characterized by mTOR mutation, loss of chromosome 1, cathepsin-K expression, and response to target therapy. [PDF]

Virchows Arch, 2023
Caliò A, Marletta S, Settanni G, Rizzo M, Gobbo S, Pedron S, Stefanizzi L, Munari E, Brunelli M, Marcolini L, Pesci A, Fratoni S, Pierconti F, Raspollini MR, Marchetti A, Doglioni C, Amin MB, Porta C, Martignoni G.   +18 more
europepmc   +1 more source

Elastase-alpha1-proteinase inhibitor complex [PDF]

, 1984
Bergmeyer, H. U., Bergmeyer, J., Graßl, M., Jochum, Marianne, Neumann, S.   +4 more
core   +1 more source

Cathepsin K as a key regulator of myocardial fibrosis in dilated cardiomyopathy and a promising therapeutic target. [PDF]

J Biol Chem
Ma L, Lu B, Si Y, Dai L, Tan M, Liu W, Sun D, Shu J, Chen C, Xiang Q, Jiang D, Wei X, Wang WE.   +12 more
europepmc   +1 more source

Treatment with an inhibitor of matrix metalloproteinase 9 or cathepsin K lengthens embryonic lower jaw bone. [PDF]

Orthod Craniofac Res, 2023
Houchen CJ, Castro B, Hahn Leat P, Mohammad N, Hall-Glenn F, Bumann EE.   +5 more
europepmc   +1 more source

CD200-CD200R affects cisplatin and paclitaxel sensitivity by regulating cathepsin K-mediated p65 NF-κB signaling in cervical cancer. [PDF]

Heliyon, 2023
Mou J, Zheng W, Wei D, Li D, Fan R, Tang Q.   +5 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source