Results 171 to 180 of about 108,576 (328)

Cathepsin L Activity Analysis Method for Evaluation of Skin Conditions of Human

, 2009
Yusuke Tahara, Akira Date, Teruhiko Makino, Tadamichi Shimizu, Masaki Yamaguchi   +4 more
openalex   +2 more sources

Role of leukocytes in hemostasis during orthotopic liver transplantation [PDF]

, 1993
Bechstein, W. O., Himmelreich, G., Huhn, D., Jochum, Marianne, Machleidt, W., Muser, M., Neuhaus, P., Riess, H., Roissaint, R.   +8 more
core   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

Participation of a Cathepsin L-Type Protease in the Activation of Caspase-3.

, 1999
Rumi Ishisaka, Toshihiko Utsumi, Tomoko Kanno, Kayo Arita, Nobuhiko Katsumura, Jitsuo Akiyama, Kozo Utsumi   +6 more
openalex   +2 more sources

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells. [PDF]

Int J Mol Sci, 2023
Abdelaziz RF, Hussein AM, Kotob MH, Weiss C, Chelminski K, Stojanovic T, Studenik CR, Aufy M.   +7 more
europepmc   +1 more source

Computational studies of copper and palladium II complex with potential anticancer activity involving topoisomerase II alpha and cathepsins B and L

, 2023
Hilário Moniz Buanar
openalex   +1 more source

Legumain drives processing of cathepsins and nuclear localisation of cathepsin L

Abstract Lysosomal proteases such as the cathepsin family and the asparaginyl endopeptidase, legumain, govern vital processes to maintain cellular proteostasis, and their dysregulation contributes to diverse pathologies. Recent studies have reported extra-lysosomal localisation of these proteases, especially in the nucleus, cytoplasm, and ...
Alexander R. Ziegler, Bangyan Xu, Bethany M. Anderson, Linghui Liu, Stephanie Luedtke, Joanna Sacharz, David A. Stroud, Nichollas E. Scott, Laura E. Edgington-Mitchell   +8 more
openaire   +1 more source

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, EarlyView.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source