Results 171 to 180 of about 16,299,323 (310)

Fighting Celiac Disease: Improvement of pH Stability of Cathepsin L In Vitro by Computational Design. [PDF]

Int J Mol Sci, 2023
Chugunov AO, Dvoryakova EA, Dyuzheva MA, Simonyan TR, Tereshchenkova VF, Filippova IY, Efremov RG, Elpidina EN.   +7 more
europepmc   +1 more source

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.

Proceedings of the National Academy of Sciences of the United States of America, 2005
G. Simmons, D. Gosalia, Andrew J Rennekamp, J. Reeves, S. Diamond, P. Bates   +5 more
semanticscholar   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Cathepsin L and transmembrane serine protease 11E mediate trypsin-independent entry of porcine deltacoronavirus into Huh7 cells. [PDF]

J Virol
Xiao W, Xiong Y, Wang Y, Li T, Chen C, Shi Y, Su G, Zhou Y, Xiao S, Fang L.   +9 more
europepmc   +1 more source

Trichinella spiralis cathepsin L damages the tight junctions of intestinal epithelial cells and mediates larval invasion. [PDF]

PLoS Negl Trop Dis, 2023
Liu RD, Meng XY, Li CL, Lin XZ, Xu QY, Xu H, Long SR, Cui J, Wang ZQ.   +8 more
europepmc   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Development of multi-epitope Cathepsin L driven short peptide vaccine against <i>Fasciola gigantica</i>. [PDF]

Front Vet Sci
Chansap S, Cheukamud W, Suthisintong T, Kueakhai P, Changklungmoa N.   +4 more
europepmc   +1 more source

Cathepsin L and acute ischemic stroke: A mini-review. [PDF]

Front Stroke, 2022
Ma L, Wu S, Gusdon AM, Chen H, Hu H, Paz AS, Aronowski J, Savarraj JP, Kitagawa RS, Choi HA, Ren XS.   +10 more
europepmc   +1 more source

The protease cathepsin L regulates Th17 cell differentiation.

Journal of Autoimmunity, 2015
Lifei Hou, J. Cooley, R. Swanson, P. Ong, R. Pike, M. Bogyo, S. Olson, E. Remold-O’Donnell   +7 more
semanticscholar   +1 more source

Effects of Kudoa thyrsites on Proximate Composition and Texture of Merluccius capensis and Zues capensis

Journal of Fish Diseases, EarlyView.
ABSTRACT Kudoa thyrsites is a myxosporean endoparasite that infects fish, frequently resulting in myoliquefaction, impacting the texture and eating quality of fish muscle. The aim of this study was to investigate the effects of K. thyrsites infection on the proximate composition and texture parameters of raw fillets from two South African economically ...
Sune St Clair Henning, Thanduxolo Phakathi   +1 more
wiley   +1 more source