Results 171 to 180 of about 29,235,414 (292)

Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

Kidney International, 2016
M. Garsen, A. Rops, H. Dijkman, Brigith K. Willemsen, T. V. van Kuppevelt, F. Russel, T. Rabelink, J. Berden, T. Reinheckel, J. van der Vlag   +9 more
semanticscholar   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Assessment of the Binding Affinity of Covalent Inhibitors of Cruzain and Cathepsin L Using Relative Binding Free Energy. [PDF]

ChemMedChem
Magno YC, Barbosa LF, Oliveira MVD, Lameira J, Montanari CA.   +4 more
europepmc   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source

<i>Trypanosoma evansi</i>: Molecular Characterization and Validation of a Cathepsin-L-like Peptidase as a Potential Therapeutic Target. [PDF]

Pathogens
Bremo A, Pérez YG, Turcios LM, Caffrey CR, Bogyo M, McKerrow JH, Gonzatti M.   +6 more
europepmc   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source

Evolutionary diversification and immunoprofiling of cathepsin L toolkit in common carp. [PDF]

Front Cell Infect Microbiol
Nayak S, Kyslík J, Majstorović J, Dobai T, Žánová V, Pecková H, Korytář T, Bartošová-Sojková P.   +7 more
europepmc   +1 more source

Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells. [PDF]

Int J Mol Sci, 2023
Abdelaziz RF, Hussein AM, Kotob MH, Weiss C, Chelminski K, Stojanovic T, Studenik CR, Aufy M.   +7 more
europepmc   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

Allergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu   +48 more
wiley   +1 more source

Cathepsin L as a Driver of Tumour Invasion and a Novel Therapeutic Target in Ovarian Cancer. [PDF]

Cancers (Basel)
Elshahri I, Ervine EHB, Musallam TK, Alajouz J, Barri M, Zinovkin DA, Pranjol MZI.   +6 more
europepmc   +1 more source