Results 181 to 190 of about 108,576 (328)

Piezo‐type mechanosensitive cation channel 1 in bone biomechanics and its multidimensional distribution characteristics in skeletal tissue

open access: yesVIEW, EarlyView.
PIEZO1 is highly correlated with mechanical stimulation, controlling bone growth and remodeling, while showing specific distribution characteristics under distinct loads. Upon dialectical review, this manuscript proposes that PIEZO1 could serve as a target for osteoporosis and a quantitative indicator for monitoring bone health in real‐time.
Chunyu Zhang, Yuehong Wang
wiley   +1 more source

6-Acylamino-penam derivatives: synthesis and inhibition of cathepsins B, L, K, and S

open access: green, 2002
Nian Zhou   +5 more
openalex   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

open access: yesVIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan   +10 more
wiley   +1 more source

Proteolysis of defensive proteins in peritonitis exudate [PDF]

open access: yes, 1991
Assfalg-Machleidt, Irmgard   +4 more
core   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

Identification of Cathepsin L as the Molecular Target of Hydroxychloroquine With Chemical Proteomics. [PDF]

open access: yesMol Cell Proteomics
Shang J   +7 more
europepmc   +1 more source

Correction: Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L. [PDF]

open access: yesSignal Transduct Target Ther, 2023
Xu X   +14 more
europepmc   +1 more source

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