The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Cutting to the core: Proteases in the tumor-bone interface and metastatic progression. [PDF]
Bhola R, Sturgeon R, Singh RK.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Targeting Cathepsin C in Cancer Metastasis: Protease Network Activation, Inflammatory Crosstalk, and Therapeutic Opportunities. [PDF]
Liu Y, Hao L, Zheng L.
europepmc +1 more source
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
When proteases reshape barriers: Basement membrane remodelling in development, wound healing and tumour progression. [PDF]
Legendre C, Dayan G, Rousselle P.
europepmc +1 more source
Diagnostic Biomarkers of Periodontitis and Peri‐Implantitis: The Past, the Present, the Future
Diagnostic biomarkers of periodontitis and peri‐implantititis from the past, through the present, and into the future. ABSTRACT In this narrative review we present our perspective on the past, present and future of periodontal and peri‐implantitis diagnostic biomarkers.
Denis F. Kinane, Başak Bıyıkoğlu
wiley +1 more source
Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions. [PDF]
Niedzielska A +5 more
europepmc +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
The causal relationship between cathepsins and ankylosing spondylitis: a two-sample Mendelian randomization study. [PDF]
Wu B +7 more
europepmc +1 more source

